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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
- 발행연도
- 2003.1
- 수록면
- 1,071 - 1,071 (1page)
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20-O-(${\beta}$-D-Glucopyranosyl)-20(S)-protopanaxadiol (IH901), an intestinal bacterial metabolite of ginseng saponins formed from ginsenosides Rb1, Rb2 and Rc, is suggested to be a potential chemopreventive agent. Here we show that IH901 induces apoptosis in human hepatoblastoma HepG2 cells. IH901 led to an early activation of procaspase-3 (6 h posttreatment), and the activation of caspase-8 became evident only later (18 h posttreatment). Caspase activation was a necessary requirement for apoptosis because caspase inhibitors significantly inhibited cell death by IH901. (omitted)
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Role of the Fas/Fas Ligand Death Receptor Pathway in Ginseng Saponin Metabolite-Induced Apoptosis in HepG2 Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
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Compound K, Ginseng Saponin Metabolite, Induces Apoptosis in Human Monocytic Leukemia cells
한국응용약물학회 추계학술발표논문집
2003 .01
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Induction of Apoptosis by a Novel Intestinal Metabolite of Ginseng Saponin via Cytochrome c Mediated Activation of Caspase-3 Protease
대한약학회 학술대회
2000 .01
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Novel ginseng saponine metabolite induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release in HepG2 cells
대한약학회 학술대회
2002 .01
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The Anti-Inflammatory Effect of IH-901 in HT-29 Cells
Molecular & cellular toxicology
2007 .01
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In vitro antioxidant properties of a ginseng intestinal metabolite IH-901
Laboratory Animal Research
2011 .09
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In vitro antioxidant properties of ginseng intestinal metabolite (IH901)
한국실험동물학회 학술발표대회 논문집
2008 .11
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An Enzyme-linked Immunosorbent for IH-901, an Active Metabolite of Ginsenoside Rb1
대한약학회 학술대회
2000 .01
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db/db 마우스에서 IH-901의 항 당뇨 활성
약학회지
2006 .01
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Radical Scavenging and Reducing Properties of IH901, Ginseng Intestinal Metabolite
한국실험동물학회 학술발표대회 논문집
2009 .04
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Induction of Human Hepatocellular Carcinoma HepG2 Cell Apoptosis by Naringin
Asian Pacific journal of cancer prevention : APJCP
2016 .01
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Establishment of a High-Throughput Screening System for Caspase-3 Inhibitors
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2000 .01
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In vivo antioxidant effects of ginseng intestinal metabolite (IH901) in endurance exercise-induced oxidative stress rat model
한국실험동물학회 학술발표대회 논문집
2008 .11
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Ginsenoside Rh2 Induces Apoptosis via Activation of Caspase-1 and -3 and Up-Regulation of Bax in Human Neuroblastoma
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
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Enterocarpam-III Induces Human Liver and Breast Cancer Cell Apoptosis via Mitochondrial and Caspase-9 Activation
Asian Pacific journal of cancer prevention : APJCP
2015 .01
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Hep88 mAb-Mediated Paraptosis-Like Apoptosis in HepG2 Cells via Downstream Upregulation and Activation of Caspase-3, Caspase-8 and Caspase-9
Asian Pacific journal of cancer prevention : APJCP
2015 .01
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20(S)-Protopanaxadiol Induces Human Breast Cancer MCF-7 Apoptosis through a Caspase-Mediated Pathway
Asian Pacific journal of cancer prevention : APJCP
2014 .01
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Kinetic Analysis of the Hepatic Uptake and Biliary Excretion of IH-901. a Potential Anticancer Agents. in Rats
대한약학회 학술대회
2002 .01
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General Pharmacology of IH-901
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2003 .01
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