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논문 기본 정보

자료유형
학술저널
저자정보
구동억 (울산의대 진단방사선과학교실)
저널정보
대한영상의학회 대한방사선의학회지 대한방사선의학회지 제33권 제4호
발행연도
1995.1
수록면
639 - 645 (7page)

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Purpose : To evaluate MR characteristics of acute disseminated encephalomyelitis (ADEM) in children, which wasconfirmed by clinical findings. Materials & Methods : The subjects were six patients, who were diagnosed byclinical findings. One subject had recurrence one year after clinical leading to one additional care with thetotal of seven. The modes of viral infections were as follows ; four cases of non-specific upper respiratory tractinfection, one of E-B virus, one of Japanese-B-encephalitis vaccination, and one of upper respiratory infection inBruton's disease. The Gd-DTPA enhanced scan was performed in all cases. MR findings were evaluated in anatomiclocation of the lesions, presence or absence of contrast enhancement, and the temporal changes were also evaluatedon follow-up MRI. Result : There were multifocal high signal intensity lesions on T2WI in all cases. The locationof lesions were basal ganglia in five, thalamus and brain stem in four, and cerebral gray and white matter andcerebellar white matter in three. Bilaterality was 77%. There were contrast enhancement in two of three cerebralcortical lesions and one of three white matter lesions. The size of lesions decreased on the first follow-up MRIwhich were done after 1 month in 4 cases, but new lesions were developed in two cases. On the second follow-up MRIwhich were done 2 months after, all lesions were decreased in size and there was no newly developed lesion.However, in one case who had recurrent similar symptom after 1 year, several new lesions developed on follow-upMRI, and it was concluded as a recurrence. Conclusion : The characteristic MR findings of ADEM were multifocalbilateral white and gray matter lesions which were high signal intensities on T2WI. The majority of lesionsimproved on follow-up MRI, but occasionally showed multiphasic pattern.

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