지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제25권 제2호
- 발행연도
- 2002.1
- 수록면
- 137 - 142 (6page)
이용수
초록· 키워드
오류제보하기
This study describes the synthesis and in vitro evaluation of 2-[3- (Cyclopenthloxy) 4-Methoxyphenyl] - Substituted-1-Isoindolinone derivatives substituted on benzene moiety of isoindoline ring for the inhibition of $TNF-{\alpha}$ production. From this study, we have found the 6-C position on isoindolinone ring is an optimal derivatization site. Among the compounds synthesized, 6-ammo-2-[3-(cyclopentyloxy)-4-methoxyphenyl]-1-isoindolinone (6) was the most potent in inhibitory activity of $TNF-{\alpha}$ production in LPS-stimulated RAW264.7 cells.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Synthesis of Novel TNF-$\alpha$ Production Inhibitors. 2- [3-(Cyclopentyloxy)-4 -methoxyphenyl] -substituted-1 -isoindolinone derivatives
대한약학회 학술대회
2001 .01
-
Synthesis and Structure-Activity Relationships of Novel Compounds for the Inhibition of TNF-$\alpha$ Production
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2000 .01
-
Synthesis of 2-(4-Methoxyphenyl)-pyrrolo〔2,1-d〕pyrido〔3,4-b〕〔1,5〕thiazepine
대한약학회 학술대회
2000 .01
-
개똥쑥에서 분리 확인된 endoperoxide ring 구조를 갖는 1,5-bis(4-methoxyphenyl)-6,7-dioxa-bicyclo[3.2.2]nonane의 항톡소포자충 효과
동의생리병리학회지
2007 .02
-
개똥쑥에서 분리 확인된 endoperoxide ring 구조를 갖는 1,5-bis(4-methoxyphenyl)-6,7-dioxa-bicyclo[3.2.2]nonane의 항톡소포자충 효과
동의생리병리학회지
2007 .01
-
Diastereoselective Synthesis of (＋)-Frontalin
대한약학회 학술대회
2002 .01
-
Synthesis of 5-Chloro-3-[4-(3-diethylaminopropoxy)benzoyl]-2(4-methoxyphenyl)benzofuran as a $\beta-Amyloid$ Aggregation
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
The Crystal Structure of a $\beta$-Allyl Type Phenylpropanoid 2-(4-allyl-2, 6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl) propan-1-ol, from the Seeds of Myristica fragrans
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1991 .01
-
Aspergillus niger에 의한 Shogaol의 생분해 메카니즘
약학회지
1983 .01
-
Type IV phosphodiesterase inhibitor(CJ-10882)의 개에 대한 2주간 경구반복투여 독성시험
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2002 .01
-
간흡충에 대하여 구충작용을 갖는 Diarylbutane류의 합성
약학회지
1985 .01
-
The investigation of photochemical reaction of phototoxic antimalarial compounds
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1980 .01
-
Biotransformation of Dehydroparadols by Aspergillus niger
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1995 .01
-
Synthesis of 4-Hydroxy-1-thiocounmarin Derivatives-1 : An Efficient Synthesis of Thioflocoumafen
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1999 .01
-
Isatin과 일염기산의 반응
약학회지
1974 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0