지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제25권 제5호
- 발행연도
- 2002.1
- 수록면
- 647 - 651 (5page)
이용수
초록· 키워드
오류제보하기
An LC/MS/MS method for the simultaneous determination of a neuroprotective agent for ischemia-reperfusion damage, KR-31378 and its N-acetyl metabolite KR-31612 in human plasma was developed. KR-31378, KR-31612 and the internal standard. KR-31543 were extracted from human plasma by liquid-liquid extraction. A reverse-phase HPLC separation was performed on Luna phenylhexyl column with the mixture of acetonitrile-5 mM ammonium formate (55:45, v/v) as mobile phase. The detection of analytes was performed using an electrospray ionization tandem mass spectrometry in the multiple reaction monitoring mode. The lower limits of quantification for KR-31378 and KR-31612 were 2.0 ng/ml. The method showed a satisfactory sensitivity, precision, accuracy, recovery and selectivity.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pharmacokinetics and Bioavailability of Oral Cephalosporins, KR-984055 and its Prodrugs, KR-999001 and KR-999002, in the Red
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
Determination of a Novel Antiangiogenic Agent KR-31831 in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry
대한약학회 학술대회
2003 .01
-
포스포디에스테라제 III의 저해물인 KR-30075의 흰쥐에서의 약물속도론
약학회지
1992 .01
-
High Performance Liquid Chromatographic Analysis of a New Proton Pump Inhibitor KR60436 and Its Active Metabolite O-Demethyl-KR60436 in Rat Plasma Samples Using Column-Switching
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2001 .01
-
새로운 Dihydropyridine 유도체, KR-30006과 KR-1008의 심장순환계 약리작용
약학회지
1989 .01
-
Metabolism of a New Neuroprotective Agent for Ischemia-Reperfusion Damage, KR-31543 in the Rats using Liquid Chromatography/Electrospray Mass Spectrometry
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2002 .01
-
Effects of Novel Potassium Channel Opener KR-30450 and its Metabolite KR-30818 on the Smooth, Muscle of the Guinea Pig
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1996 .01
-
In Vitro Metabolism of a New Cardioprotective Agent, KR-33028 in the Human Liver Microsomes and Cryopreserved Human Hepatocytes
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
-
Characterization of the Physicochemical Properties of KR-31378
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
Effects of a New Neuroprotective Agent KR-31378 on Liver Cytochrome P450s in Male Sprague Dawley Rats
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
흰쥐에서의 관상동맥 결찰/재관류도 유도된 심근경색에 대한 칼륨통로 개방제 KR-30450의 약리학적 효과
약학회지
1997 .01
-
결과에 대한 지식의 상대적 빈도와 지연간격유형이 운동학습애 미치는 영향 벼교
한국전문물리치료학회지
1997 .01
-
Neuroprotective effect of KR-31378 in cortical cell culture and in brain ischemia-reperfusion model
대한약학회 학술대회
2001 .01
-
Enzyme Kinetic Study of a New Cardioprotective Agent, KR-32570 using Human Liver Microsomes and Recombinant CYP Isoforms
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
High-Performance Liquid Chromatographic Analysis, Blood Partition and Protein ′binding of a New Neuroprotective Agent for Ischemia-reperfusion Damage, KR-31378
대한약학회 학술대회
2001 .01
-
The Effects of KR-10876, a new Quinolone Antimicrobial Agent, on the Central Nervous System
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1993 .01
-
Selectivity of the optical isomers of KR30031 on MDR reversal activity and cardiotoxicity
대한약학회 학술대회
2002 .01
-
Kinetic Characterization of Brain Distribution for KR-31378 in Rats
대한약학회 학술대회
2002 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0