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자료유형
학술저널
저자정보
Mishima, Satoshi (Api Co., Ltd. Research Institute) Gu, Yeun-Hwa (Graduate School of Health Science, Suzuka University of Medical Science) Saito, Kiyoto (Graduate School of Health Science, Suzuka University of Medical Science) Yamashita, Takenori (Graduate School of Health Science, Suzuka University of Medical Science) Maruyama, Hiroe (Api Co., Ltd. Research Institute) Inoue, Makoto (Faculty of pharmaceutical science, Nagoya City University) Ahn, Kyoo-Seok (Department of Pathology, College of Oriental medicine, Institute of Oriental medicine, Kyunghee University)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제4권 제3호
발행연도
2004.1
수록면
163 - 170 (8page)

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The effect of immune activation by Echinacea purpurea was investigated by measuring total immunoglobulin (Ig) G, IgM. and the radioprotective effect of immune activation by Echinacea purpurea was investigated by measuring T lymphocyte subsets in the peripheral blood of mice following whole body irradiation. Echinacea purpurea activated macrophages to stimulate $IFN-{\gamma}$ production in association with the secondary activation of T lymphocytes, resulting in a decrease in IgG and IgM production. Cytokines released from macrophages in mouse peripheral blood after Echinacea purpurea administration activated helper T cells to proliferate. In addition, activated macrophages in association with the secondary T lymphocyte activation increased $IFN-{\gamma}$ production and stimulated proliferation of cytotoxic T cells and suppressor T cells, indicating the activation of cell-mediated immune responses.

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