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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 317 - 323 (7page)
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초록· 키워드
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Quercetin and kaempferol, two well-known flavonols, were chemically conjugated with glucose to produce the corresponding flavonol glucosides, and the following biological activities were evaluated for cosmeceutical development: antioxidant activity, ability to increase collagen synthesis, and moisturizing activity. Among the synthetic flavonol glucosides, quercetin-3-O-${\beta}$-D-glucoside significantly enhanced collagen synthesis (60 %) compared to quercetin. Kaempferol-3,7-di-O-${\beta}$-D-glucoside showed promising skin-moisturizing effects, inducing a sixfold increase in the expression of aquaporin-3. Thus, both quercetin-3-O-${\beta}$-D-glucoside and kaempferol-3,7-di-O-${\beta}$-D-glucoside were shown to possess interesting biological activities which warrant their further development as cosmetic ingredients.
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