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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 376 - 385 (10page)
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Recent discoveries of brain tumor-related genes and fast advances in genomic testing technologies have led to the era of molecular diagnosis of brain tumor. Molecular profiling of brain tumor became the significant step in the diagnosis, the prediction of prognosis and the treatment of brain tumor. Because traditional molecular testing methods have limitations in time and cost for multiple gene tests, next-generation sequencing technologies are rapidly introduced into clinical practice. Targeted sequencing panels using these technologies have been developed for brain tumors. In this article, focused on pediatric brain tumor, key discoveries of brain tumor-related genes are reviewed and cancer panels used in the molecular profiling of brain tumor are discussed.
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참고문헌 (82)
참고문헌 신청
Araki A / 2016 / Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma / Acta Neuropathol Commun 4:88
Bai RY / 2015 / Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis / Neuro Oncol 17:545~554
Bavle AA / 2016 / Applications of genomic sequencing in pediatric CNS tumors / Oncology (Williston Park) 30:411~423
Behling F / 2016 / Frequency of BRAF V600E mutations in 969 central nervous system neoplasms / Diagn Pathol 11:55
Bentley DR / 2008 / Accurate whole human genome sequencing using reversible terminator chemistry / Nature 456:53~59
Bai RY / 2015 / Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis / Neuro Oncol 17:545~554
Bavle AA / 2016 / Applications of genomic sequencing in pediatric CNS tumors / Oncology (Williston Park) 30:411~423
Behling F / 2016 / Frequency of BRAF V600E mutations in 969 central nervous system neoplasms / Diagn Pathol 11:55
Bentley DR / 2008 / Accurate whole human genome sequencing using reversible terminator chemistry / Nature 456:53~59
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