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자료유형
학술저널
저자정보
Pak, Pyo June (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University) Go, Eun Byeol (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University) Hwang, Min Hee (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University) Lee, Dong Gun (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University) Cho, Mi Ju (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University) Joo, Yong Hoon (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University) Chung, Namhyun (Department of Biosystems Engineering, College of Life Sciences and Biotechnology, Korea University)
저널정보
한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제59권 제2호
발행연도
2016.1
수록면
145 - 147 (3page)

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Recently, conjugates of medicinal herb-derived bioflavonoids, such as quercetin, and gold nanoparticles (GNPs) have gained attention as targeted drug delivery systems. In the present study, because quercetin is an important flavonoid with anti-cancer, anti-inflammatory, and anti-oxidant properties, GNP-quercetin complexes (GNPQs) were synthesized to investigate possible adverse effects such as cytotoxicity. We found that while quercetin was cytotoxic, GNPQs were not cytotoxic towards the RAW 264.7 and THP-1 cell lines. Therefore, GNPQs may serve as a potential drug delivery system for cancer treatment.

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