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논문 기본 정보

자료유형
학술저널
저자정보
Jeong, Jong-Hyun (College of Bioscience & Biotechnology, Kangwon National University) Lee, Ji-Won (College of Bioscience & Biotechnology, Kangwon National University) Kim, Kyoung-Su (Department of Agricultural Biotechnology, Seoul National University) Kim, Ju-Sung (Oriental Bio-herb Research Institute, Kangwon National University) Han, Sang-No (Samsung Herb Medicine Co., Ltd) Yu, Chang-Yeon (College of Bioscience & Biotechnology, Kangwon National University) Lee, Ju-Kyong (College of Bioscience & Biotechnology, Kangwon National University) Kwon, Yong-Soo (College of Pharmacy, Kangwon National University) Kim, Myong-Jo (College of Bioscience & Biotechnology, Kangwon National University)
저널정보
한국응용생명화학회 Applied Biological Chemistry Applied Biological Chemistry 제53권 제1호
발행연도
2010.1
수록면
33 - 38 (6page)

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This study was performed to evaluate the antioxidant and antimicrobial activities from the methanol extracts of the root and stem of Hippophae rhamnoides and their further partitioned fractions including hexane, ethyl acetate, butanol, and water. Antioxidant activities of the plant parts were measured by 1,1-dephenyl-2-picryl-hydrazyl (DPPH), superoxide dismutase (SOD)-like activity, and ferric thiocyanate (FTC) assays, and compared to standard antioxidants of butylated hydroxyl anisole, butylated hydroxyl toluene, $\alpha$-tocopherol, and ascorbic acid. Antimicrobial activity of the plant extracts and fractions were evaluated by determining the minimum inhibitory concentration values. DPPH assay showed that the overall strong antioxidant activities from the methanol extracts and fractions. The values of SOD-like activities in hexane fractions of the root and stem were close to the measurement of a reference, ascorbic acid at 1,000 ppm. The methanol extract of the root in FTC assay showed a remarkable antioxidant and free radical scavenging activity. The extracts and fractions of the root and stem showed better antimicrobial activity than compared antimicrobial agents, (+)-catechin, ketoconazol, and mycostantin. This study indicates that the plant root and stem contain a variety of compounds contributing to antioxidant and antimicrobial activity, which could be used for food additives and the development of useful natural compounds.

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