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자료유형
학술저널
저자정보
Kim, Hoon (Department of Obstetrics and Gynecology, Seoul National University Hospital) Kim, Seul Ki (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Yu, Eun Jeong (Department of Obstetrics and Gynecology, Seoul National University Hospital) Lee, Jung Ryeol (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Jee, Byung Chul (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital) Suh, Chang Suk (Department of Obstetrics and Gynecology, Seoul National University Hospital) Kim, Seok Hyun (Department of Obstetrics and Gynecology, Seoul National University Hospital)
저널정보
대한생식의학회 Clinical and experimental reproductive medicine : CERM Clinical and experimental reproductive medicine : CERM 제42권 제4호
발행연도
2015.1
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136 - 142 (7page)

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Objective: Smoking has been reported to harm nearly every organ of the body, but conflicting results have been reported regarding the effects of smoking on assisted conception. In this prospective cohort study, we aimed to investigate the prevalence of positive urinary cotinine tests in infertile couples and whether cotinine positivity was associated with infertility treatment outcomes. Methods: A qualitative urinary cotinine test was administered to 127 couples who underwent in vitro fertilization (IVF, n=92) or intrauterine insemination (IUI, n=35). Results: The overall prevalence of positive urinary cotinine test was 43.3% (55/127) in the male partners and 10.2% (13/127) in the female partners with similar prevalence rates in both genders in the IUI and IVF groups. Semen characteristics, serum markers of ovarian reserve, and number of retrieved oocytes were comparable among cotinine-positive and cotinine-negative men or women (with the exception of sperm count, which was higher among cotinine-positive men). The results of urinary cotinine tests in infertile couples were not associated with IVF and IUI outcomes. Conclusion: The presence of cotinine in the system, as indicated by a positive urinary cotinine test, was not associated with poorer outcomes of infertility treatment.

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