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자료유형
학술저널
저자정보
Shin, Young Seob (Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine) Yoon, Yong sik (Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine) Lim, Seok-Byung (Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine) Yu, Chang Sik (Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine) Kim, Tae Won (Department of Medical Oncology, Asan Medical Center, University of Ulsan College of Medicine) Chang, Heung Moon (Department of Medical Oncology, Asan Medical Center, University of Ulsan College of Medicine) Park, Jin-hong (Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine) Ahn, Seung Do (Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine) Lee, Sang-Wook (Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine) Choi, Eun Kyung (Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine) Kim, Jin Cheon (Department of Surgery, Asan Medical Center, University of Ulsan Col) Kim, Jong Hoon
저널정보
대한방사선종양학회 Radiation oncology journal : ROJ Radiation oncology journal : ROJ 제34권 제3호
발행연도
2016.1
수록면
177 - 185 (9page)

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Purpose: To investigate whether preoperative chemoradiotherapy (PCRT) followed by local excision (LE) is feasible approach in clinical T2N0 rectal cancer patients. Materials and Methods: Patients who received PCRT and LE because of clinical T2 rectal cancer within 7 cm from anal verge between January 2006 and June 2014 were retrospectively analyzed. LE was performed in case of a good clinical response after PCRT. Patients' characteristics, treatment record, tumor recurrence, and treatment-related complications were reviewed at a median follow-up of 49 months. Results: All patients received transanal excision or transanal minimally invasive surgery. Of 34 patients, 19 patients (55.9%) presented pathologic complete response (pCR). The 3-year local recurrence-free survival and disease free-survival were 100.0% and 97.1%, respectively. There was no recurrence among the patients with pCR. Except for 1 case of grade 4 enterovesical fistula, all other late complications were mild and self-limiting. Conclusion: PCRT followed by an LE might be feasible as an alternative to total mesorectal excision in good responders with clinical T2N0 distal rectal cancer.

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