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학술저널
저자정보
Madani, Seyed-Hamid (Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences) Rahmati, Ali (Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences) Sadeghi, Edris (Cancer Research Center, Kermanshah University of Medical Sciences) Khazaei, Sedighe (Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences) Sadeghi, Masoud (Medical Biology Research Center, Kermanshah University of Medical Sciences) Payandeh, Mehrdad (Medical Biology Research Center, Kermanshah University of Medical Sciences) Amirifard, Nasrin (Cancer Research Center, Kermanshah University of Medical Sciences)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제17호
발행연도
2015.1
수록면
7,755 - 7,758 (4page)

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Background: There is increasing evidence that HER2-neu is an important biomarker in gastric carcinomas (GC) and gastroesophageal junction (GEJ) adenocarcinomas. The aim of this study was to evaluate HER2-neu expression and also some clinicopathological features of these neoplasms. Materials and Methods: We selected 211 paraffin-embedded blocks, 193 GC and 18 GEJ. Then 4 micron sections were prepared for staining with hematoxylin and eosin and also for IHC (Her2-neu). The Chi-square test was used for significance between expression of HER2-neu and clinicopathological parameters. Results: In patients with advanced cancer of GC and GEJ, HER2-neu overexpression was more associated with the intestinal cancer subtype. Conclusions: This could be a guide to new complementary therapy for affected patients.

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