Is Early Detection of Colon Cancer Possible with Red Blood Cell Distribution Width?

Ay, Serden; Eryilmaz, Mehmet Ali; Aksoy, Nergis; Okus, Ahmet; Unlu, Yasar; Sevinc, Baris

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자료유형: 학술저널

저자정보: Ay, Serden (General Surgery, Malazgirt State Hospital) Eryilmaz, Mehmet Ali (General Surgery Clinic, Konya Training and Research Hospital) Aksoy, Nergis (General Surgery Clinic, Konya Training and Research Hospital) Okus, Ahmet (Department of General Surgery, Faculty of Medicine, Mevlana Universit) Unlu, Yasar (Pathology Clinic, Konya Training and Research Hospital) Sevinc, Baris (General Surgery Clinic, Konya Training and Research Hospital)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제2호

발행연도: 2015.1

수록면: 753 - 756 (4page)

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Background: Red cell distribution width (RDW) is one of the standard parameters with blood cell counts. Much previous research has indicated that it increases in cases of systemic inflammation or cardiametabolic incident. However, information on the relation of RDW with solid tumors causing systemic inflammation is limited. In the present research, we examined the relation of RDW with malignant and benign lesions of the colon. Materials and Methods: 115 patients with colon polyps (group 1), and 30 with colon cancer (group 2) who were diagnosed histopathologically in our clinic between January 2010-January 2013 were scanned retrospectively. Patients with anemia, hematologic diseases and active inflammation were excluded. RDW, mean corpuscular volume (MCV), hemoglobin (Hgb) and platelet (Plt) measurements were recorded and their relations with the malignant and benign lesions of the colon were examined. Results: Both groups were similar in age and gender distribution. RDW values of patients with colon cancer were significantly higher than the patients with colon polyp (p=0,01). No significant differences were detected between the two groups in terms of MCV and Plt values (p>0,05). Conclusions: RDW can be used as an early warning biomarker for solid colon tumors. Further prospective research is required on the relations of cheap and easily measured RDW parameters with colon malignancies.

#Colorectal cancer #colon polyp #red cell distribution width #associations

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