IOTA Simple Rules in Differentiating between Benign and Malignant Adnexal Masses by Non-expert Examiners

Tinnangwattana, Dangcheewan; Vichak-ururote, Linlada; Tontivuthikul, Paponrad; Charoenratana, Cholaros; Lerthiranwong, Thitikarn; Tongsong, Theera

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자료유형: 학술저널

저자정보: Tinnangwattana, Dangcheewan (Department of Obstetrics and Gynecology, Chiang Mai University) Vichak-ururote, Linlada (Department of Obstetrics and Gynecology, Chiang Mai University) Tontivuthikul, Paponrad (Department of Obstetrics and Gynecology, Chiang Mai University) Charoenratana, Cholaros (Department of Obstetrics and Gynecology, Chiang Mai University) Lerthiranwong, Thitikarn (Department of Obstetrics and Gynecology, Chiang Mai University) Tongsong, Theera (Department of Obstetrics and Gynecology, Chiang Mai University)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제9호

발행연도: 2015.1

수록면: 3,835 - 3,838 (4page)

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Objective: To evaluate the diagnostic performance of IOTA simple rules in predicting malignant adnexal tumors by non-expert examiners. Materials and Methods: Five obstetric/gynecologic residents, who had never performed gynecologic ultrasound examination by themselves before, were trained for IOTA simple rules by an experienced examiner. One trained resident performed ultrasound examinations including IOTA simple rules on 100 women, who were scheduled for surgery due to ovarian masses, within 24 hours of surgery. The gold standard diagnosis was based on pathological or operative findings. The five-trained residents performed IOTA simple rules on 30 patients for evaluation of inter-observer variability. Results: A total of 100 patients underwent ultrasound examination for the IOTA simple rules. Of them, IOTA simple rules could be applied in 94 (94%) masses including 71 (71.0%) benign masses and 29 (29.0%) malignant masses. The diagnostic performance of IOTA simple rules showed sensitivity of 89.3% (95%CI, 77.8%; 100.7%), specificity 83.3% (95%CI, 74.3%; 92.3%). Inter-observer variability was analyzed using Cohen's kappa coefficient. Kappa indices of the four pairs of raters are 0.713-0.884 (0.722, 0.827, 0.713, and 0.884). Conclusions: IOTA simple rules have high diagnostic performance in discriminating adnexal masses even when are applied by non-expert sonographers, though a training course may be required. Nevertheless, they should be further tested by a greater number of general practitioners before widely use.

#Adnexal mass #the IOTA simple rules #non-expert examiner, ultrasound #benign ovarian tumor

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