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논문 기본 정보

자료유형
학술저널
저자정보
Lim, Kwang-Ryeol (Department of Plastic and Reconstructive Surgery, Dong-A University School of Medicine) Cho, Jeong-Min (Department of Plastic and Reconstructive Surgery, Dong-A University School of Medicine) Yoon, Chung-Min (Department of Plastic and Reconstructive Surgery, Dong-A University School of Medicine) Lee, Keun-Cheol (Department of Plastic and Reconstructive Surgery, Dong-A University School of Medicine) Lee, Sang-Yun (Ellium Women's Hospital) Ju, Mi-Ha (Department of Pathology, Dong-A University School of Medicine)
저널정보
대한성형외과학회 Archives of plastic surgery : APS Archives of plastic surgery : APS 제45권 제1호
발행연도
2018.1
수록면
14 - 22 (9page)

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Background Liposuction has become one of the most frequently performed procedures in the field of aesthetic surgery. Fat embolism syndrome after liposuction can easily be overlooked or underestimated; however, occasionally, fulminating fat embolism syndrome can develop and lead to a critical situation within 2-3 days after lipoplasty. Changes over time in the amount of circulating fat particles and the histology of major organs have not yet been studied. Methods This study was conducted using 18 male Sprague-Dawley rats aged 12 weeks and weighing 500-628 g (average, 562 g). Fifteen rats were used as the experimental group and 3 as the control group. Under general anesthesia, tumescent-technique liposuction was performed at the lateral flank areas and abdomen for 1 hour. Blood, lung, and brain tissue specimens were obtained at 1 hour, 1 day, and 2 days after the liposuction procedure. Results The average number of fat particles in the blood samples was 25,960/dL at 1 hour, 111,100/dL at 24 hours, and 21,780/dL at 48 hours. The differences between study groups were statistically significant. Both intravascular and extravascular fat particles with inflammation were seen in all 15 rats, as were inflammatory cell infiltration, hemorrhage, and consolidation with shrinkage of the lung alveoli. Conclusions These results imply that there is a strong possibility of fat embolism syndrome after liposuction in real clinical practice, and the first 24-48 hours after the operation were found to be the most important period for preventing pulmonary embolism and progression to fulminating fat embolism syndrome.
#Liposuction #Adipose tissue #Embolism #Fat embolism syndrome

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참고문헌 (19)

참고문헌 신청
Wang HD / 2008 / Fat embolism syndromes following liposuction / Aesthetic Plast Surg 32:731~736 Crossref Coleman WP 3rd / 2000 / A history of dermatologic surgery in the United States / Dermatol Surg 26:5~11 Crossref Rohrich RJ / 2000 / The increasing popularity of cosmetic surgery procedures: a look at statistics in plastic surgery / Plast Reconstr Surg 106:1363~1365 Crossref Glover P / 1999 / Fat embolism / Crit Care Resusc 1:276~284 google schola Levy D / 1990 / The fat embolism syndrome: a review / Clin Orthop Relat Res (261):281~286 google schola

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