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자료유형
학술저널
저자정보
Wang, Jessica S. (Department of Plastic Surgery, Center for Wound Healing, MedStar Georgetown University Hospital) Louw, Ryan P. Ter (Department of Plastic Surgery, Center for Wound Healing, MedStar Georgetown University Hospital) DeFazio, Michael V. (Department of Plastic Surgery, Center for Wound Healing, MedStar Georgetown University Hospital) McGrail, Kevin M. (Department of Neurosurgery, MedStar Georgetown University Hospital) Evans, Karen K. (Department of Plastic Surgery, Center for Wound Healing, MedStar Georgetown University Hospital)
저널정보
대한성형외과학회 Archives of plastic surgery : APS Archives of plastic surgery : APS 제46권 제4호
발행연도
2019.1
수록면
365 - 370 (6page)

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The syndrome of the trephined is a neurologic phenomenon that manifests as sudden decline in cognition, behavior, and sensorimotor function due to loss of intracranial domain. This scenario typically occurs in the setting of large craniectomy defects, resulting from trauma, infection, and/or oncologic extirpation. Cranioplasty has been shown to reverse these symptoms by normalizing cerebral hemodynamics and metabolism. However, successful reconstruction may be difficult in patients with complex and/or hostile calvarial defects. We present the case of a 48-year-old male with a large cranial bone defect, who failed autologous cranioplasty secondary to infection, and developed rapid neurologic deterioration leading to a near-vegetative state. Following debridement and antibiotic therapy, delayed cranioplasty was accomplished using a polyetheretherketone (PEEK) implant with free chimeric latissimus dorsi/serratus anterior myocutaneous flap transfer for vascularized resurfacing. Significant improvements in cognition and motor skill were noted in the early postoperative period. At 6-month follow-up, the patient had regained the ability to speak, ambulate and self-feed-correlating with evidence of cerebral/ventricular re-expansion on computed tomography. Based on our findings, we advocate delayed alloplastic implantation with total vascularized soft tissue coverage as a viable alternative for reconstructing extensive, hostile calvarial defects in patients with the syndrome of the trephined.

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