갑상선 결절에서 세침흡인검사와 동결조직검사의 의의

김재원; 이장원; 배성호; 고국진; 윤석영; 김영모

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자료유형: 학술저널

저자정보: 김재원 (인하대학교 의과대학 이비인후과학교실) 이장원 (인하대학교 의과대학 이비인후과학교실) 배성호 (인하대학교 의과대학 이비인후과학교실) 고국진 (인하대학교 의과대학 이비인후과학교실) 윤석영 (인하대학교 의과대학 이비인후과학교실) 김영모 (인하대학교 의과대학 이비인후과학교실)

저널정보: 대한두경부종양학회 대한 두경부 종양 학술지 대한 두경부 종양 학술지 제20권 제2호

발행연도: 2004.1

수록면: 143 - 146 (4page)

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Background and Object: The role of fine needle aspiration cytology (FNAC) and frozen section (FS) in management of thyroid neoplasms continues to generate considerable controversy. We reviewed our current experience to determine the clinical utility of FNAC and FS in our surgical management and investigated reliability of FNAC and FS in planning the extent of thyroid resection. Material and Method: 212 patients who had operations for thyroid disease from May 1996 to November 2003 were included our retrospective study. FNAC was undertaken in 175 patients and FS was done in 148 patients. Result: The sensitivity and specificity of FNAC were 72.1% and 100%, respectively, and those of FS were 67.2% and 100%. The results of FNAC were benign (n=72) , malignancy (n=31), indeterminate (n=9), and nondiagnostic (n=63). The results of FS were benign (n=95), and malignancy (n=53). The 9 indeterminate cases on FNAC were benign (n=6) and malignancy (n=3) on final pathology, and benign (n=7) and malignancy (n=2) on FS. The false negative of FNAC were micro papillary carcinoma (n=6) and follicular carcinoma (n=6). The false negative of FS were micropapillary carcinoma (n=10) and follicular carcinoma (n=2). Conclusion: When results of FNAC are interpreted as indeterminate, FS is a valuable tool. FS is helpful in determining the extent of thyroidectomy when results of FNAC were follicular neoplasm. However we always concerned about micropapillary carcinoma and follicular carcinoma although FNAC and FS were benign.

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