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논문 기본 정보

자료유형
학술저널
저자정보
Bang, In-Chul (Department of Marine Biotechnology, Soonchunhyang University) Cho, Young-Sun (Department of Aquaculture, Pukyong National University) Lee, Il-Rho (Department of Marine Biotechnology, Soonchunhyang University) Nam, Yoon-Kwon (Department of Aquaculture, Pukyong National University)
저널정보
한국수생태학회 한국하천호수학회지 한국하천호수학회지 제40권 제4호
발행연도
2007.1
수록면
489 - 494 (6page)

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Transcriptional modulation of metallothionein (MT) during acute metal exposures (cadmium, copper or zinc) was examined in fry of Hemibarbus mylodon, a threatened fish species in Korean peninsula. Viability of H. mylodon fry was most affected by copper exposure (up to 79% of mortality at 1 ppm for 48 hours) and considerably by cadmium exposure (21 to 54% of mortality). On the other hand, Zn showed the least adverse effect on the viability (0 to 13% of mortality) of this species. Based on the semi-quantitative RT-PCR analysis, the stimulation of MT mRNA in response to metal exposures followed generally in a dose-dependent fashion where cadmium was the most potent inducer for the induction of MT transcripts in fry (up to more than 5-fold) while the lowest response was observed in zinc-exposed group (2-fold at maximum). From the exposure using environmentally realistic doses of cadmium (0 to 0.05 ppm for 24 hours), MT expression at mRNA level was also sensitively modulated toward upregulation up to more than 3-fold as relative to non-exposed control. Results from the present study would be a good basis for understanding the adaptive capacity and stress physiology of this endangered fish species during metal pollution.

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