지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.9
- 수록면
- 210 - 216 (7page)
이용수
초록· 키워드
오류제보하기
The purpose of this study was to evaluate GDH & Toxin (GDT) tests for the identification of the presence of Clostridioides difficile (C. difficile) as well as to detect whether any toxin was present in the feces of patients suspected of diarrhea associated with C. difficile. Data related to the results of toxin and culture (TC) tests and GDT tests conducted on patients with diarrhea and suspected CDI between January 2017 and august 2018, positive test rates, patient ages and sexes, whether the patients were hospitalized, and turnaround time (TAT) were analyzed retrospectively. Of the 7,554 total tests conducted for CDI diagnosis, 1,010 TC tests (14.9%) were positive, while 92 GDT tests (12.0%) were positive. Of these positive cases, 815 (80.7%) identified through TC test and 80 (87%) identified through GDT test were inpatients. also, among the patients with positive test results, 497 (49.2%) diagnosed through TC test and 45 (48.9%) diagnosed through GDT test were aged 61 years or older. The total time required to complete a TC test was 83.6 hours, while the time required for a GDT test was 11.2 hours, equating to an approximately three-day difference between the two tests. The detection of toxin-producing C. difficile is important in CDI diagnosis, but the commonly used Enzymeimmunoassay (EIA) toxin tests with low sensitivity result in delayed CDI diagnosis time. Therefore, primary screening tests for CDI diagnosis using the GDT method and secondary tests using additional methods are considered most effective.
목차
서론
재료 및 방법
결과
고찰
REFERENCES
참고문헌 (14)
참고문헌 신청
Bartlett JG / 2002 / Antibiotic-associated diarrhea / N Engl J Med 346:334~339
조혜정 / 2010 / 소아에서 발생한 Clostridium difficile 관련 질환의 역학과 임상양상: 지역사회감염과 원내감염의 비교 / Pediatric Gastroenterology, Hepatology & Nutrition 13(2):146~153
Dubberke ER / 2012 / Burden of Clostridium difficile on the healthcare system / Clin Infect Dis 55:88~92
Hensgens MP / 2012 / Clostridium difficile infection in the commnity:a zoonotic disease? / Clin Microbiol Infect 18:635~645
전성란 / 2016 / Clinical Characterization of Clostridium difficile Infection in Elderly Patients / 대한소화기학회지 67(2):61~63
조혜정 / 2010 / 소아에서 발생한 Clostridium difficile 관련 질환의 역학과 임상양상: 지역사회감염과 원내감염의 비교 / Pediatric Gastroenterology, Hepatology & Nutrition 13(2):146~153
Dubberke ER / 2012 / Burden of Clostridium difficile on the healthcare system / Clin Infect Dis 55:88~92
Hensgens MP / 2012 / Clostridium difficile infection in the commnity:a zoonotic disease? / Clin Microbiol Infect 18:635~645
전성란 / 2016 / Clinical Characterization of Clostridium difficile Infection in Elderly Patients / 대한소화기학회지 67(2):61~63
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UCI(KEPA) : I410-ECN-0101-2020-510-001305983