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논문 기본 정보

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학술저널
저자정보
Chung Hae-Sun (Department of Laboratory Medicine Ewha Womans University College of Medicine Seoul Korea.) Park Jeong Su (Department of Laboratory Medicine Seoul National University Bundang Hospital Seongnam Korea.) Shin Bo-Moon (Department of Laboratory Medicine Sanggye Paik Hospital School of Medicine Inje University Seoul Ko) Yoo Hyeon Mi (Infection Control Office Inje University Sanggye Paik Hospital Seoul Korea.) Kim Heejung (Department of Laboratory Medicine Yongin Severance Hospital Yonsei University College of Medicine Y) Cho Jihyun (Department of Laboratory Medicine Wonkwang University Hospital Iksan Korea.) Lee Chae Hoon (Department of Laboratory Medicine College of Medicine Yeungnam University Daegu Korea.) Ryoo Nam Hee (Department of Laboratory Medicine Keimyung University School of Medicine Daegu Korea.) Kim Jae-Seok (Department of Laboratory Medicine Kangdong Sacred Heart Hospital Hallym University College of Medic) Chung Jae-Woo (Department of Laboratory Medicine Dongguk University Ilsan Hospital Goyang Korea.) Hong Ki Ho (Department of Laboratory Medicine Severance Hospital Yonsei University College of Medicine Seoul Ko) Kim You Sun (Department of Internal Medicine Seoul Paik Hospital Inje University College of Medicine Seoul Korea) Cho Young-Seok (Department of Internal Medicine Seoul St. Mary's Hospital College of Medicine The Catholic Universi)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.5
발행연도
2022.2
수록면
1 - 11 (11page)
DOI
10.3346/jkms.2022.37.e38

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Background: The interest in Clostridioides difficile infection (CDI) has increased, and the choice of assays became wider since the first national survey in Korea on CDI diagnosis in 2015. We conducted a survey of the domestic CDI assays with more varied questions to understand the current situation in Korea. Methods: In April 2018, about 50 questions on the current status of CDI assays and details on implementation and perceptions were written, and a survey questionnaire was administered to laboratory medicine specialists in 200 institutions. Results: One-hundred and fifty institutions responded to the questionnaire, of which 90 (60.0%) including one commercial laboratory, performed CDI assays. The toxin AB enzyme immunoassay (toxin AB EIA), nucleic acid amplification test (NAAT), and C. difficile culture, glutamate dehydrogenase assay, alone or in combination with other assays, were used in 75 (84.3%), 52 (58.4%), 35 (36.0%), and 23 (25.8%), respectively, and 65 (73.0%) institutions performed a combination of two or more assays. The sensitivity of toxin AB EIA was more negatively perceived, and that on specificity was more positively perceived. The perception of sensitivity and specificity of NAAT was mostly positive. Perception on the algorithm test projected it as useful but in need of countermeasures. Sixty-three (73.3%) institutions responded that they performed surveillance on CDI. Conclusion: This study provides useful evidence on the current status of CDI laboratory diagnosis in Korea as well as on items that require improvement and is thought to aid in standardizing and improving the CDI laboratory diagnosis in Korea.
#Clostridioides difficile Infection #Laboratory Diagnosis #Toxin AB Enzyme Immunoassay #Nucleic Acid Amplification Test #Culture #Glutamate Dehydrogenase #Survey

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