지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.99 No.4
- 발행연도
- 2020.10
- 수록면
- 197 - 204 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: The use of prophylactic central neck dissection (PCND) and the extent of thyroid surgery in clinically node-negative (cN0) papillary thyroid carcinoma (PTC) are controversial. This study aimed to investigate whether the extent of thyroid surgery influences the prognosis of patients with PTC with central lymph node metastasis (N1a), which was cN0 but pathologically confirmed after PCND.
Methods: This was a single-center retrospective study using medical records. Patients who underwent thyroid surgery with PCND for the treatment of PTC between 2004 and 2019 were included. Predictive factors and local recurrence rates were analyzed.
Results: Of 2,274 patients with cN0 PTC, 436 were confirmed to have pathologic N1a disease after PCND. Among them, 340 patients (78.0%) underwent total thyroidectomy (TT) and 96 patients (22.0%) underwent less than TT. Of the 374 patients who were followed up for ＞6 months, 5 (1.3%) experienced recurrence. The 15-year recurrence-free survival (RFS) rate was 98.2%. No clinicopathologic factor was predictive of tumor recurrence. RFS tended to be lower in patients who underwent less than TT than in those who underwent TT; however, the difference was not statistically significant.
Conclusion: Our study showed low recurrence rates in patients with cN0 PTC pathologically confirmed as N1a after PCND. The RFS did not differ according to the extent of thyroid surgery. Considering the low recurrence rate and the surgical morbidity associated with thyroid surgery, less than TT with PCND may be considered for patients with cN0 unilateral PTC even with a pathologic staging of N1a after PCND.
Methods: This was a single-center retrospective study using medical records. Patients who underwent thyroid surgery with PCND for the treatment of PTC between 2004 and 2019 were included. Predictive factors and local recurrence rates were analyzed.
Results: Of 2,274 patients with cN0 PTC, 436 were confirmed to have pathologic N1a disease after PCND. Among them, 340 patients (78.0%) underwent total thyroidectomy (TT) and 96 patients (22.0%) underwent less than TT. Of the 374 patients who were followed up for ＞6 months, 5 (1.3%) experienced recurrence. The 15-year recurrence-free survival (RFS) rate was 98.2%. No clinicopathologic factor was predictive of tumor recurrence. RFS tended to be lower in patients who underwent less than TT than in those who underwent TT; however, the difference was not statistically significant.
Conclusion: Our study showed low recurrence rates in patients with cN0 PTC pathologically confirmed as N1a after PCND. The RFS did not differ according to the extent of thyroid surgery. Considering the low recurrence rate and the surgical morbidity associated with thyroid surgery, less than TT with PCND may be considered for patients with cN0 unilateral PTC even with a pathologic staging of N1a after PCND.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
Cooper DS / 2006 / Management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 16:109~142
American Thyroid Association (ATA)Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer / 2009 / Revised American Thyroid Associat ion management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19:1167~1214
Haugen BR / 2016 / 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer : the American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer / Thyroid 26:1~133
Haddad RI / 2019 / NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for thyroid carcinoma, version 2.2019 / National Comprehensive Cancer Network, Inc
Amit M / 2018 / Association of lymph node density with survival of patients with papillary thyroid cancer / JAMA Otolaryngol Head Neck Surg 144:108~114
American Thyroid Association (ATA)Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer / 2009 / Revised American Thyroid Associat ion management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19:1167~1214
Haugen BR / 2016 / 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer : the American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer / Thyroid 26:1~133
Haddad RI / 2019 / NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for thyroid carcinoma, version 2.2019 / National Comprehensive Cancer Network, Inc
Amit M / 2018 / Association of lymph node density with survival of patients with papillary thyroid cancer / JAMA Otolaryngol Head Neck Surg 144:108~114
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Surgical Extent of Clinically Node Negative Papillary Thyroid Carcinoma in Patients with Pathologic N1a after Prophylactic Central Node Dissection
대한외과학회 학술대회 초록집
2021 .05
-
The effectiveness of prophylactic ipsilateral central neck dissection (CND) in patients who underwent total thyroidectomy for clinically node-negative papillary thyroid carcinoma (PTC)
대한외과학회 학술대회 초록집
2019 .10
-
20세 이하 갑상선 유두암 환자의 임상 특징과 치료 결과
대한이비인후-두경부외과학회지
2015 .01
-
Relationship between Initial Thyroid Operation and the Location of Locoregional Recurrence in Papillary Thyroid Cancer: a Single Tertiary Center Experience
The Journal of Endocrine Surgery
2019 .01
-
Identifying Risk Factors of Lateral Lymph Node Recurrence for Clinicallynode-Negative Papillary Thyroid Cancer
대한외과학회 학술대회 초록집
2018 .11
-
Number of Tumor Foci as a Predictive Factor of Recurrence in Papillary Thyroid Carcinoma
대한외과학회 학술대회 초록집
2022 .11
-
The Future of Thyroid Surgery
The Journal of Endocrine Surgery
2020 .01
-
Thyroid Cancer Surgery
대한외과학회 학술대회 초록집
2022 .11
-
Thyroid : Cons
대한임상종양학회 학술대회지
2015 .02
-
갑상선유두상암에서 예방적 중심경부림프절제술은 생략할 수 있는가?
대한 두경부 종양 학술지
2018 .01
-
Analysis of Treatment Results after Thyroid Lobectomy with Prophylactic Ipsilateral Central Neck Lymph Node Dissection for Low-Risk Papillary Thyroid Carcinoma: A Single Institute Experience
대한이비인후-두경부외과학회지
2015 .01
-
Cohexisting Medullary and Papillary Thyroid Cancer
The Journal of Endocrine Surgery
2017 .01
-
Identifying Risk Factors for Recurrence for Papillary Thyroid Cancer Patients who Underwent Modified Radical Neck Dissection
대한외과학회 학술대회 초록집
2018 .11
-
Thyroid Hemiagenesis Associated with Papillary Thyroid Carcinoma
International Journal of Thyroidology
2016 .01
-
Importance of Regular Follow-Up Examination during Active Surveillance: a Case of Anaplastic Transformation of Papillary Thyroid Microcarcinoma
International Journal of Thyroidology
2016 .01
-
갑상선 유두암과 동반된 갑상선 MALT 림프종 1예
임상이비인후과
2018 .01
-
Central Lymph Node Ratio Predicts Recurrence in Patients with N1b Papillary Thyroid Carcinoma
대한외과학회 학술대회 초록집
2022 .11
-
2 cm 이하의 저위험군 갑상선유두암 환자에서 갑상선엽절제술과 갑상선전절제술의 비교연구
International Journal of Thyroidology
2019 .01
-
The Effect of Prophylactic Central Neck Dissection During Hemithyroidectomy on Locoregional Recurrence in Patients With Papillary Thyroid Carcinoma: A Meta-Analysis
Clinical and Experimental Otorhinolaryngology
2020 .01
-
Postoperative Thyroid-Stimulating Hormone Levels Did Not Affect Recurrence after Thyroid Lobectomy in Patients with Papillary Thyroid Cancer
Endocrinology and Metabolism
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2020-514-001293295