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논문 기본 정보

자료유형
학술저널
저자정보
Seo Hye Park (Inha University School of Medicine) Hojong Jun (Inha University School of Medicine) Seong Kyu Ahn (Inha University School of Medicine) Jinyoung Lee (Inha University School of Medicine) Sung-Lim Yu (Inha University School of Medicine) Sung Keun Lee (Inha University School of Medicine) Jung-Mi Kang (Gyeongsang National University College of Medicine) Hyunwoo Kim (Korea Centers for Disease Control and Prevention) Hee-Il Lee (Korea Centers for Disease Control and Prevention) Sung-Jong Hong (Chung-Ang University College of Medicine) Byoung-Kuk Na (Gyeongsang National University College of Medicine) Young Yil Bahk (Konkuk University) Tong-Soo Kim (Inha University School of Medicine)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.58 No.5
발행연도
2020.10
수록면
543 - 550 (8page)

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Mosquitoes are globally distributed and important vectors for the transmission of many human diseases. Mosquito control is a difficult task and the cost of preventing mosquito-borne diseases is much lower than that for curing the associated diseases. Thus, chemical control remains the most effective tool for mosquito. Due to the long-term intensive use of insecticides to control mosquito vectors, resistance to most chemical insecticides has been reported. This study aimed to investigate the relationship between insecticide resistance and target site mutation of L1014 kdr and G119 ace alleles in 5 species/species group of mosquitoes (Aedes vexans, Ae. albopictus, Anopheles spp., Culex pipiens complex, and Cx. tritaeniorhynchus) obtained from 6 collection sites. For Anopheles spp., the proportion of mosquitoes with mutated alleles in L1014 was 88.4%, homozygous resistant genotypes were observed in 46.7%, and heterozygous resistant genotypes were observed in 41.8%. For the Cx. pipiens complex and Cx. tritaeniorhynchus species, homozygous resistant genotypes were found in 25.9% and 9.8%, respectively. However, target site mutation of L1014 in the Ae. vexans nipponii and Ae. albopictus species was not observed. Anopheles spp., Cx. pipiens complex, and Cx. tritaeniorhynchus mosquitoes were resistant to deltamethrin and chlorpyriphos, whereas Ae. vexans nipponii and Ae. albopictus were clearly susceptible. We also found a correlation between the resistance phenotype and the presence of the L1014 kdr and G119 ace mutations only in the Anopheles spp. population. In this study, we suggest that insecticide resistance poses a growing threat and resistance management must be integrated into all mosquito control programs.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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UCI(KEPA) : I410-ECN-0101-2020-513-001565080