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논문 기본 정보

자료유형
학술저널
저자정보
Jung Min Lee (Seoul National University College of Medicine) Hongbeom Kim (Seoul National University College of Medicine) Jae Seung Kang (Seoul National University College of Medicine) Yoonhyeong Byun (Seoul National University College of Medicine) Yoo Jin Choi (Seoul National University College of Medicine) Hee Ju Sohn (Seoul National University College of Medicine) Youngmin Han (Seoul National University College of Medicine) Wooil Kwon (Seoul National University College of Medicine) Jin-Young Jang (Seoul National University College of Medicine)
저널정보
대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.100 No.6
발행연도
2021.6
수록면
320 - 328 (9page)

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초록· 키워드

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Purpose: Laparoscopic distal pancreatectomy (LDP) is widely performed but its efficacy and safety are not established for malignant lesions. This study was aimed to compare outcomes of LDP and open distal pancreatectomy (ODP) in pancreatic ductal adenocarcinoma (PDAC).
Methods: Patients who underwent distal pancreatectomy for PDAC between 2009 and 2017 were enrolled. The preoperative clinical stage was evaluated and propensity score matching (PSM) was performed using age, sex, The American Joint Committee on Cancer 8th clinical T stage, and other organ involvement.
Results: In 186 patients enrolled, 35 (18.8%) received LDP. The ODP group showed larger tumor size and frequent involvement of other organs in preoperative images. However, after PSM, these differences were balanced. R0 resection (90.5% vs. 94.3%, P = 0.730), harvested lymph nodes (14.3 vs. 12.6, P = 0.380) and pathologic T stage (P = 0.474) were comparable between ODP and LDP groups, respectively. LDP demonstrated shorter operation time, less postoperative pain, and shorter hospitalization (14.4 days vs. 11.1 days, P = 0.026). In terms of long-term oncologic outcomes, median overall survival (32 months vs. 28 months, P = 0.724) and disease-free survival (18 months vs. 19 months, P = 0.926) were comparable.
Conclusion: LDP demonstrated better short-term outcomes and comparable long-term outcomes compared with ODP. LDP is a safe and feasible procedure for PDAC.

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INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES

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