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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.6
- 수록면
- 82 - 82 (1page)
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n-3 PUFA has protective effects of inflammation and insulin resistance (IR), while n-6 PUFA promotes the development of IR. In this study, we hypothesized that partial dietary replacement high-fat (lard) by different n-6/n-3 PUFA containing beef tallow (BT) would prevent inflammatory response and endoplasmic reticulum (ER) stress in a genetically diabetic mice. Experimental db/db mice were assigned four groups as normal diet, high-fat diet (HFD), HFD+n-3 balanced beef tallow (HFD+n3B, n-6/n-3=0.9), HFD+n-3 enhanced beef tallow (HFD+n3E, n-6/n-3=0.4). After 6 weeks of dietary intervention, 1 mg/kg of PBS or tunicamycin (TM) were injected by i.p. for 12 hours.
In the absence of TM, high-fat replacement with n3E suppressed serum TC and non-HDL-C ^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10561272');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
In the absence of TM, high-fat replacement with n3E suppressed serum TC and non-HDL-C ^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10561272');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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