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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 한국수산과학회 양식분과 한국수산과학회 양식분과 학술대회 2021 Conference on the Future Technology of Fisheries Science [3개 분과 공동개최]
- 발행연도
- 2021.4
- 수록면
- 320 - 320 (1page)
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The malectin is a membrane-bound endoplasmic reticulum (ER) resistant lectin family protein that recognizes and binds Glc2-N-glycan. Malectin plays a role in protein quality control by binding with misfolded proteins in the endoplasmic reticulum and preventing their folding pathway by directing them to the ER-associated degradation (ERAD) pathway. Malectin’s structure is similar to carbohydrate-binding modules (CBMs) of bacterial glycosyl hydrolases. In this study, we analyzed the molecular features and the expression pattern of the malectin from clownfish (Amphiprion clarkii). The cDNA and protein sequence of malectin were identified from A.clarkki (AcMLEC) and analyzed molecular wise by using in-silico tools. The qPCR was performed to determine the tissue-specific mRNA expression of MLEC in healthy A.clarkii. Temporal expression profile of AcCav-1 upon immune challenged with poly I: C, LPS, and Vibrio harveyi were investigated in blood and gill. For the control group, fish w ... 전체 초록 보기
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