지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 187 - 194 (8page)
이용수
초록· 키워드
오류제보하기
Platelets are derived from fragments formed in the cytoplasm of bone marrow megakaryocytes. Platelet count (PLT) can be altered by factors such as platelet production, destruction, and inflammation. In a previous study, the significant single nucleotide polymorphisms (SNP) were reported by the genome-wide association study (GWAS) for PLT in Koreans. In this study, it was confirmed whether significant SNPs were replicated in the HEXA (The Health Examinees) cohort. As a result, the SNPs of the THPO (rs6141), BAK1 (rs210314, rs9296095), GGNBP1 (rs75080135), ACAD10 (rs6490294), and ABCC4 (rs4148441) were significantly correlated with PLT (P < 10<SUP>-8</SUP>). At the same time, it was confirmed that the direction of influence was the same according to the genotype. In conclusion, it can be seen that common SNPs are associated with the platelet count regardless of the cohort for Koreans.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Astle WJ / 2016 / The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease / Cell 167:1415~1429
Bain BJ / 1996 / Ethnic and sex differences in the total and differential white cell count and platelet count / J Clin Pathol 49:664~666
Bessman JD / 1981 / Mean platelet volume. The inverse relation of platelet size and count in normal subjects, and an artifact of other particles / Am J Clin Pathol 76:289~293
Buckley MF / 2000 / A novel approach to the assessment of variations in the human platelet count / Thromb Haemost 83:480~484
Chami N / 2014 / Lessons and Implications from Genome-Wide Association Studies(GWAS)Findings of Blood Cell Phenotypes / Genes(Basel) 5:51~64
Bain BJ / 1996 / Ethnic and sex differences in the total and differential white cell count and platelet count / J Clin Pathol 49:664~666
Bessman JD / 1981 / Mean platelet volume. The inverse relation of platelet size and count in normal subjects, and an artifact of other particles / Am J Clin Pathol 76:289~293
Buckley MF / 2000 / A novel approach to the assessment of variations in the human platelet count / Thromb Haemost 83:480~484
Chami N / 2014 / Lessons and Implications from Genome-Wide Association Studies(GWAS)Findings of Blood Cell Phenotypes / Genes(Basel) 5:51~64
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Mean Platelet Volume and Mean Platelet Volume/Platelet Count Ratio in Chronic Urticaria
Annals of Dermatology
2019 .01
-
Effectiveness of Platelet Function Analyzer-100 for Laboratory Detection of Anti-Platelet Drug-Induced Platelet Dysfunction
Annals of Laboratory Medicine
2019 .01
-
Pre-treatment Elevated Platelet Count Associates with HER2 Overexpression and Prognosis in Patients with Breast Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Characteristics of blood tests in patients with acute cerebral infarction who developed symptomatic intracranial hemorrhage after intravenous administration of recombinant tissue plasminogen activator
Clinical and Experimental Emergency Medicine
2019 .01
-
Evaluation of Platelet Indices in Lung Cancer Patients
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Effects and treatment applications of polymeric nanoparticles on improving platelets’ storage time: a review of the literature from 2010 to 2020
Blood Research
2021 .12
-
Replication Study of Genome Wide Association Study of Sleep Duration in Korean Association Resources Cohort
대한의생명과학회지
2024 .06
-
Characterization of the distinct mechanism of agonist-induced canine platelet activation
Journal of Veterinary Science
2019 .01
-
Platelet count recovery after intravenous immunoglobulin predicts a favorable outcome in children with immune thrombocytopenia
Blood Research
2016 .01
-
Association between the platelet-to-hemoglobin ratio and survival-to-discharge in comatose patients with out-of-hospital cardiac arrest with an initial shockable rhythm: a retrospective cohort study
대한응급의학회지
2024 .06
-
Thapsigargin Induces Platelet Aggregation, thereby Releases Lactate Dehydrogenase from Rat Platelets
대한의생명과학회지
2021 .09
-
Expanded Impacts of Platelet Functions: Beyond Hemostasis and Thrombosis
Annals of Laboratory Medicine
2019 .01
-
Age-period-cohort Analysis of Healthy Lifestyle Behaviors Using the National Health and Nutrition Survey in Japan
예방의학회지
2020 .01
-
The Korea Cohort Consortium: The Future of Pooling Cohort Studies
예방의학회지
2022 .09
-
Prognostic Impact of Increased Perioperative Platelet Count in Gastric Cancer Patients
대한외과학회 학술대회 초록집
2019 .05
-
Platelet-rich plasma, platelet derivatives, and their therapeutic importance in veterinary medicine
Journal of Biomedical and Translational Research
2022 .12
-
Liver transplantation of a patient with extreme thrombocytopenia - A case report -
Anesthesia and Pain Medicine
2021 .01
-
The anti-platelet activity of panaxadiol fraction and panaxatriol fraction of Korean Red Ginseng in vitro and ex vivo
Journal of Ginseng Research
2023 .09
-
Temporal Variability of Platelet Reactivity Phenotype: Another Barrier to Personalized Antiplatelet Strategy Guided by Platelet Function Testing
Korean Circulation Journal
2019 .01
-
클로피도그렐 또는 티카그렐러로 치료받는 환자에서 혈소판 수와 특성이 혈소판 반응성에 미치는 영향
대한내과학회지
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0