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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 384 - 391 (8page)
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초록· 키워드
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The recent appearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people around the world and caused a global pandemic of coronavirus disease 2019 (COVID-19). It has been suggested that uncontrolled, exaggerated inflammation contributes to the adverse outcomes of COVID-19. In this review, we summarize our current understanding of the innate immune response elicited by SARS-CoV-2 infection and the hyperinflammation that contributes to disease severity and death. We also discuss the immunological determinants behind COVID-19 severity and propose a rationale for the underlying mechanisms.
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참고문헌 (67)
참고문헌 신청
Abers, M. S. / 2021 / An immune-based biomarker signature is associated with mortality in COVID-19 patients / JCI Insight 6:e144455
Arunachalam, P. S. / 2020 / Systems biological assessment of immunity to mild versus severe COVID-19infection in humans / Science 369:1210~1220
Bastard, P. / 2020 / Autoantibodies against type I IFNs in patients with life-threatening COVID-19 / Science 370:eabd4585
Bernardes, J. P. / 2020 / Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 / Immunity 53:1296~1314
Blanco-Melo, D. / 2020 / Imbalanced host response to SARS-CoV-2 drives development of COVID-19 / Cell 181:1036~1045
Arunachalam, P. S. / 2020 / Systems biological assessment of immunity to mild versus severe COVID-19infection in humans / Science 369:1210~1220
Bastard, P. / 2020 / Autoantibodies against type I IFNs in patients with life-threatening COVID-19 / Science 370:eabd4585
Bernardes, J. P. / 2020 / Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 / Immunity 53:1296~1314
Blanco-Melo, D. / 2020 / Imbalanced host response to SARS-CoV-2 drives development of COVID-19 / Cell 181:1036~1045
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Immunological Sequelae of SARS-CoV-2 Pregnancy Infection and Long COVID-19
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One-health Approach in the Post-COVID-19 Era: Focusing on Animal Infection
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Innate Immunity : Historical Aspects and Involvement in Fighting SARS-CoV-2
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