Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses

Kyun-Do Kim; Insu Hwang; Ku Keunbon; Sumin Lee; Seong-Jun Kim; Kim Chonsaeng

Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses

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Type: Academic journal

Author: Kyun-Do Kim (한국화학연구원) Insu Hwang (한국화학연구원) Ku Keunbon (한국화학연구원) Sumin Lee (한국화학연구원) Seong-Jun Kim (한국화학연구원) Kim Chonsaeng (한국화학연구원)

Journal: 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제30권 제8호 KCI Accredited Journals SCOPUS

Published: 2020.1

Pages: 1,109 - 1,115 (7page)

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Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses

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The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally, and the WHO has declared this outbreak a pandemic. Vaccines are an effective way to prevent the rapid spread of COVID-19. Furthermore, the immune response against SARS-CoV-2 infection needs to be understood for the development of an efficient and safe vaccine. Here, we review the current understanding of vaccine targets and the status of vaccine development for COVID-19. We also describe host immune responses to highly pathogenic human coronaviruses in terms of innate and adaptive immunities.

#COVID-19 #SARS-CoV-2 #Coronavirus #vaccine #immune response

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Zhou P / 2020 / A pneumonia outbreak associated with a new coronavirus of probable bat origin / Nature 579:270~273

Zumla A / 2016 / Coronaviruses-drug discovery and therapeutic options / Nat. Rev. Drug Discov 15:327~347

Cheng VC / 2007 / Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection / Clin. Microbiol. Rev 20:660~694

Chan JF / 2015 / Middle East respiratory syndrome coronavirus : another zoonotic betacoronavirus causing SARS-like disease / Clin. Microbiol. Rev 28:465~522

이정윤 / 2019 / Middle East Respiratory Syndrome Coronavirus-Encoded Accessory Proteins Impair MDA5-and TBK1-Mediated Activation of NF-κB / Journal of Microbiology and Biotechnology 29(8):1316~1323

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김균도

Affiliation Korea Research Institute of Chemical Technology

Fields Natural Science > Biology Natural Science > Chemistry

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황인수

Affiliation 한국화학연구원