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논문 기본 정보

자료유형
학술저널
저자정보
Lee Keun Hwa (Department of Microbiology Hanyang University College of Medicine Seoul Korea.) Heo Sang Taek (Department of Internal Medicine Jeju National University School of Medicine Jeju Korea.) Jeong Seung Uk (Department of Internal Medicine Jeju National University School of Medicine Jeju Korea.) Kim Mi-yeon (Department of Internal Medicine Jeju National University School of Medicine Jeju Korea.) Jeong Woo Seong (Department of Internal Medicine Jeju National University School of Medicine Jeju Korea.) Hyun Chang Lim (Department of Pathology Jeju National University School of Medicine Jeju Korea.) Kim Young-Kyu (Department of Surgery Jeju National University School of Medicine Jeju Korea.) Yoo Jeong Rae (Department of Internal Medicine Jeju National University School of Medicine Jeju Korea.)
저널정보
대한감염학회 Infection and Chemotherapy Infection and Chemotherapy 제52권 제4호
발행연도
2020.1
수록면
621 - 625 (5page)

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Scrub typhus present with a variety clinical manifestations caused by Orientia tsutsugamushi, it is sometimes accompanied by severe complications. The clinical course of this complication is not well clear. Herein, we first report a case with acute cholangitis and acalculous cholecystitis caused by the Boryong genotype of O. tsutsugamushi. A 82-year-old woman presented with fever and acute abdominal pain on the right upper quadrant. Initially, the patient showed an abnormality of liver enzymes of cholestatic pattern. An acute cholangitis and cholecystitis were suspected on the enhanced computed tomography (CT), and emergent endoscopic retrograde cholangiopancreatography (ERCP) performed. However, neither ERCP nor CT detected common bile duct stones or sludge. The patient's illness progressed despite bile drainage and antibiotic therapy. On the fifth day in hospital, an immunofluorescence IgG assay for O. tsutsugamushi was positive, and the patient newly developed a skin rash and an eschar lesion on the right abdomen. The polymerase chain reaction amplification of Orientia genes from blood and bile was positive, genotype of both samples was identified the Boryong type. The presentation of scrub typhus as an acute cholangitis is not reported till now. In endemic areas, scrub typhus would be considered a rare etiology of acute cholangitis.

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