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논문 기본 정보

자료유형
학술저널
저자정보
Chi-Son Chang (Sungkyunkwan University School of Medicine) Soo-young Oh (Sungkyunkwan University) Yunsun Choi (Sungkyunkwan University) 김서연 (성균관의대 산부인과학교실) 이청아 (성균관의대 산부인과) 김미나 (성균관의대 산부인과) 성지희 (성균관대학교 의과대학 산부인과학교실) Sanghoon Lee (Sungkyunkwan University) Suk-Joo Choi (Sungkyunkwan University School of Medicine) Jeong-Meen Seo (Division of Pediatric Surgery Department of Surgery Samsung Medical Center) Cheong-Rae Roh (Department of Obstetrics and Gynecology Samsung Medical Center Sungkyunkwan University School of Me)
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제64권 제1호
발행연도
2021.1
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42 - 51 (10page)

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ObjectiveWe investigated prenatal sonographic characteristics of esophageal atresia (EA) with advancing gestation. We focusedon the degree of polyhydramnios and the stomach shape. MethodsThis study included 27 EA cases (EA group) and 81 idiopathic polyhydramnios cases (non-EA group). The non-EAgroup consisted of cases without any fetal structural anomaly, musculoskeletal disorder, chromosomal abnormality,or maternal diabetes. Both groups included only singleton pregnancies. Amniotic fluid index (AFI) and width/length(W/L) ratio as well as the product of width and length (W×L) of stomach were serially assessed during gestation andcompared between the 2 groups. To predict EA using W/L ratio and W×L, receiver operating characteristic curveanalysis was performed. ResultsPolyhydramnios was evident in 77.8% of EA cases. We observed 25.9% and 22.2% EA cases with an absent stomachand a small visible stomach, respectively. After 28 weeks, the EA group manifested significantly higher AFI than thenon-EA group. After 32 weeks, W/L ratio in the EA group tended to be lower than that in the non-EA group (32?36weeks: 1.36 vs. 1.72, P=0.092; >36 weeks: 1.43 vs. 1.63, P=0.024). To predict EA, the calculated area under the curve forW/L ratio was 0.651 after 32 weeks. The diagnosis of EA using a cut-off value of W/L ratio <1.376 showed sensitivity,specificity, positive likelihood ratio, and negative likelihood ratio to be 84.6%, 52.9%, 1.796, and 0.081, respectively. ConclusionA low W/L ratio of stomach after 32 weeks with progressive idiopathic polyhydramnios may be used to predict EA.

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