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논문 기본 정보

자료유형
학술저널
저자정보
Yoshihide Kanno (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Tetsuya Ohira (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Yoshihiro Harada (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Shinsuke Koshita (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Takahisa Ogawa (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Hiroaki Kusunose (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Yoshiki Koike (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Taku Yamagata (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Toshitaka Sakai (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Kaori Masu (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Keisuke Yonamine (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Kazuaki Miyamoto (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Megumi Tanaka (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Tomohiro Shimada (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Fumisato Kozakai (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Kazuki Endo (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Haruka Okano (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Daichi Komabayashi (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Takeshi Shimizu (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Shohei Suzuki (Department of Gastroenterology Sendai City Medical Center Sendai Japan) Kei Ito (Department of Gastroenterology Sendai City Medical Center Sendai Japan)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제54권 제3호
발행연도
2021.1
수록면
340 - 347 (8page)

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초록· 키워드

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Background/Aims: The aim of this study was to evaluate the safety of sedation with propofol as an alternative to benzodiazepinedrugs in outpatient endoscopy. Methods: In this prospective study, examinees who underwent outpatient endoscopy under propofol sedation and submitted a nextdayquestionnaire with providing informed consent were evaluated. Periprocedural acute responses, late adverse events within 24hours, and examinee satisfaction were evaluated. Results: Among the 4,122 patients who received propofol in the 17,978 outpatient-based endoscopic examinations performedbetween November 2016 and March 2018, 2,305 eligible examinees (esophagogastroduodenoscopy for 1,340, endoscopicultrasonography for 945, and total colonoscopy for 20) were enrolled, and their responses to a questionnaire were analyzed. Themean propofol dose was 69.6±24.4 mg (range, 20?200 mg). Diazepam, midazolam, and/or pentazocine in combination withpropofol was administered to 146 examinees. Mild oxygen desaturation was observed in 59 examinees (2.6%); and mild bradycardia,in 2 (0.09%). Other severe reactions or late events did not occur. After eliminating 181 invalid responses, 97.7% (2,065/2,124) of thepatients desired propofol sedation in future examinations. Conclusions: Propofol sedation was found to be safe-without severe adverse events or accidents-for outpatient endoscopy on thebasis of the patients’ next-day self-evaluation. Given the high satisfaction level, propofol sedation might be an ideal tool for painlessendoscopic screening.
#Cancer screening #Endoscopic ultrasonography #Esophagogastroduodenoscopy #Propofol #Sedation

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참고문헌 (15)

참고문헌 신청
Delgado AAA / 2019 / Propofol vs traditional sedatives for sedation in endoscopy : a systematic review and meta-analysis / World J Gastrointest Endosc 11:573~588 google schola Grant SA / 2000 / Blood propofol concentration and psychomotor effects on driving skills / Br J Anaesth 85:396~400 google schola Riphaus A / 2006 / Quality of psychomotor recovery after propofol sedation for routine endoscopy : a randomized and controlled study / Endoscopy 38:677~683 google schola Basavana Goudra / 2017 / Association between Type of Sedation and the Adverse Events Associated with Gastrointestinal Endoscopy: An Analysis of 5 Years’ Data from a Tertiary Center in the USA / Clinical Endoscopy 50(2):161~169 dbpia Hermanus H. B. Vaessen / 2016 / Considerable Variability of Procedural Sedation and Analgesia Practices for Gastrointestinal Endoscopic Procedures in Europe / Clinical Endoscopy 49(1):47~55 google schola

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