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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 196 - 202 (7page)
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Background: Postoperative cognitive dysfunction (POCD) is a common perioperative complication. The definitive causes of POCD have not been identified, but depth of anesthesia or sedation has been reported to influence POCD. The purpose of the present study was to assess the possible effect of the level of sedation on POCD at 1 week after surgery under spinal anesthesia in elderly patients. Methods: We included 48 patients aged over 60 years, who were scheduled for elective knee and hip joint surgery under spinal anesthesia. Those patients were randomly allocated to one of the 2 groups: deep sedation group and light sedation group. The depth of sedation was monitored by entropy and observer’s assessment of alertness/sedation (OAA/S) score. Cognitive function was assessed by 5 neurocognitive tests before and at 1 week after surgery. A postoperative deficit was defined as a postoperative decrement to preoperative score greater than 1 standard deviation on any test. A patient whose postoperative performance deteriorated by 1 or more standard deviations on 2 or more tests was classified as having experienced POCD. Results: POCD occurred in 7 patients (28%) in the deep sedation group and in 4 patients (17.4%) in the light sedation group. The incidence of the POCD was not significantly different between the 2 groups. Conclusions: We were unable to detect a significant association between the depth of sedation and the presence of POCD at 1 week after surgery under spinal anesthesia.
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참고문헌 (25)
참고문헌 신청
Newman MF / 2001 / Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery / Stroke 32:2874~2881
Monk TG / 2008 / Predictors of cognitive dysfunction after major noncardiac surgery / Anesthesiology 108:18~30
Evered L / 2011 / Postoperative cognitive dysfunction is independent of type of surgery and anesthetic / Anesth Analg 112:1179~1185
Rasmussen LS / 2003 / Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients / Acta Anaesthesiol Scand 47:260~266
Williams-Russo P / 1995 / Cognitive effects after epidural vs general anesthesia in older adults. A randomized trial / JAMA 274:44~50
Monk TG / 2008 / Predictors of cognitive dysfunction after major noncardiac surgery / Anesthesiology 108:18~30
Evered L / 2011 / Postoperative cognitive dysfunction is independent of type of surgery and anesthetic / Anesth Analg 112:1179~1185
Rasmussen LS / 2003 / Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients / Acta Anaesthesiol Scand 47:260~266
Williams-Russo P / 1995 / Cognitive effects after epidural vs general anesthesia in older adults. A randomized trial / JAMA 274:44~50
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