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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 130 - 144 (15page)
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Adipose tissue is composed of diverse cell types and plays a major role in energy homeostasis and inflammation at the local and systemic levels. Adipose tissue serves as the main site for vitamin D storage and is among the most important extraskeletal targets of vitamin D which can modulate multiple aspects of adipose tissue biology. Vitamin D may exert inhibitory or stimulatory effects on adipocyte differentiation depending on cell type, stage of differentiation, and the treatment time point. Moreover, vitamin D controls energy metabolism in adipose tissue by affecting fatty acid oxidation, expression of uncoupling proteins, insulin resistance, and adipokine production. Adipose tissue inflammation can have a significant impact on the metabolic disorders often associated with obesity, and vitamin D can modulate the inflammatory response of immune cells and adipocytes within the adipose tissue. This review discusses the role of adipose tissue in vitamin D metabolism, as well as the regulatory role of vitamin D in adipocyte differentiation, adipose tissue energy metabolism, and inflammation, thereby providing insights into the importance of vitamin D in adipose tissue biology.
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참고문헌 (95)
참고문헌 신청
Luo L / 2016 / Adipose tissue in control of metabolism / J Endocrinol 231:R77~R99
Ding C / 2012 / Vitamin D signalling in adipose tissue / Br J Nutr 108:1915~1923
Institute of Medicine / 2011 / Dietary reference intakes for calcium and vitamin D / The National Academies Press
Haddad JG / 1993 / Human plasma transport of vitamin D after its endogenous synthesis / J Clin Invest 91:2552~2555
Holick MF / 2003 / Primer on the metabolic bone diseases and disorders of mineral metabolism / American Society for Bone and Mineral Research :129~137
Ding C / 2012 / Vitamin D signalling in adipose tissue / Br J Nutr 108:1915~1923
Institute of Medicine / 2011 / Dietary reference intakes for calcium and vitamin D / The National Academies Press
Haddad JG / 1993 / Human plasma transport of vitamin D after its endogenous synthesis / J Clin Invest 91:2552~2555
Holick MF / 2003 / Primer on the metabolic bone diseases and disorders of mineral metabolism / American Society for Bone and Mineral Research :129~137
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