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논문 기본 정보

자료유형
학술저널
저자정보
Park Eun Ji (Research Institute of Rehabilitation Medicine Yonsei University College of Medicine Seoul Korea.Dep) Kim Yong Wook (Research Institute of Rehabilitation Medicine Yonsei University College of Medicine Seoul Korea.Dep) Nam Hyo Suk (Department of Neurology Yonsei University College of Medicine Seoul Korea.) Choi Hyo Seon (Department of Rehabilitation Medicine Nowon Eulji Medical Center Eulji University Seoul Korea.) Kim Deog Young (Research Institute of Rehabilitation Medicine Yonsei University College of Medicine Seoul Korea.Dep)
저널정보
대한뇌신경재활학회 뇌신경재활 뇌신경재활 제14권 제2호
발행연도
2021.1
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1 - 8 (8page)

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초록· 키워드

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It is unclear how these brain lesions fit into the language processing in acute stroke. In this study, we aimed to investigate the neuroanatomical lesion related to language processing in acute stage of stroke patients using voxel-based lesion-symptom mapping (VLSM). 73 acute first-ever post-stroke patients were enrolled in this retrospective study, who had undertaken brain magnetic resonance imaging (MRI) and Korean version of the Western Aphasia Test within 1 month from onset. Each voxel was compared with aphasia quotient and subtest scores as dependent variables using VLSM. The aphasia group showed significantly much more involvement of extra-nuclear area, insula, inferior frontal gyrus and superior temporal gyrus compared to non-aphasia group. The deficit of spontaneous speech domain was associated with the inferior parietal lobule, inferior and middle frontal gyrus and insula. The insular cortex, inferior parietal lobule, inferior frontal gyrus, middle frontal gyrus and superior temporal gyrus were related to deficit of comprehension. The inferior parietal lobule, insula, precentral gyrus, inferior frontal gyrus were related to the deficit of repetition. The deficit of naming was related to inferior parietal lobule, insula and inferior frontal gyrus. In conclusion, VLSM from early MRI imaging study after stroke may be useful to understand the language process network and establish early rehabilitation strategies after stroke.

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