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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 117 - 117 (1page)
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An individual’s genetic background may influence their biological responses to nutrients and their risk of subsequent adverse health outcomes that are linked to nutritional status. Identifying genes that are associated with nutrient utilization has great potential to improve human health and personalize nutritional intakes. Personalized nutrition approaches are highly relevant to iron homeostasis as both iron deficiency and excess impact risk of chronic disease and adverse health outcomes. Large screening studies have evaluated risk of elevated body iron stores as a function of ancestry and have found that individuals of Asian, particularly East Asian ancestry have the highest risk of elevated body iron stores. This finding is surprising given that the most common genetic mutations associated with iron overload (C282Y and H63D) are nearly absent among Asian individuals. Individuals of East Asian ancestry may also develop iron overload-related diseases such as diabetes at a lower body mass index than typically o ... 전체 초록 보기
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