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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 534 - 534 (1page)
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Colorectal cancer (CRC) is a malignancy of the colon or rectum. Early resection permitted by early detection is the best treatment, and chemotherapy is another main treatment, particularly for patients with advanced CRC. A well-known thymidylate synthase (TS) inhibitor, 5-fluorouracil (5-FU), has frequently been prescribed to CRC patients; however, drug resistance is a critical limitation of its clinical application. Coptidis Rhizoma extract (CRE) can abolish this 5-FU resistance, we explored the efficacy and underlying mechanisms of CRE in 5-FU-resistant (HCT116/ R) and parental HCT116 (HCT1^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10669138');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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Role of Protein Kinases on Activation of Nrf2/Keap1/ARE Signaling Pathway by Sulforaphane and Licochalcone A in HCT116 Human Colon Cancer Cells
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