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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 636 - 636 (1page)
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이 논문의 연구 히스토리 (2)
2021
Effects of Electrical Stimulation on Enhancing the Cytotoxic Activity and Half-life of Natural Killer Cells
Minseon LEE
,
Soonjo KWON
한국생물공학회 학술대회
2021.10
학술대회자료
Strategies for Enhancing the Expansion and Half-life of Natural Killer Cells Using 3D Microcarrier Culture
Minseon LEE
,
Soonjo KWON
한국생물공학회 학술대회
2021.04
학술대회자료
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Natural killer (NK) cells are responsible for the effector function against tumors in innate immune system, predominantly mediated by the secretion of lytic granules containing granzyme and perforin at immunological synapses. However, strategies for NK cell-immunotherapy still should be developed due to the existing immune evasion of tumors by protecting cells from granule uptake and being resistant to NK cell-mediated killing. In this study, we designed a direct current electrical stimulation (ES) system using platinum electrodes as a strategy for enhancing cytotoxic activity and half-life of NK cells for efficient immunotherapy. ES effects have been studied in tissue engineering for bone healing and stem cells by targeting calcium signaling on cell differentiation and migration. Exposure to electrical field cou ... 전체 초록 보기
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Magneto-Activation of Natural Killer Cells for the Treatment of Solid Tumors
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