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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 588 - 598 (11page)
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The most common metastatic site of breast cancer is the bone. Metastatic bone disease can alter the integrity of the bone and cause serious complications, thereby greatly reducing health-related quality of life and leading to high medical costs. Although diagnostic methods and treatments for bone metastases (BM) are improving, some patients with early breast cancer who are at high risk of BM are not diagnosed early enough, leading to delayed intervention. Moreover, whole-body scintigraphy cannot easily distinguish BM from nonmalignant bone diseases. To circumvent these issues, specific gene and protein biomarkers are being investigated for their potential to predict, diagnose, and evaluate breast cancer prognosis. In this review, we summarized the current biomarkers associated with BM in breast cancer and their role in clinical applications to assist in the diagnosis and treatment of BM in the future.
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참고문헌 (73)
참고문헌 신청
Willett WC / 2014 / World Cancer Report 2014 / International Agency for Research on Cancer :124~133
Siegel RL / 2017 / Cancer statistics, 2017 / CA Cancer J Clin 67:7~30
Malvezzi M / 2012 / European cancer mortality predictions for the year 2012 / Ann Oncol 23:1044~1052
Yardley DA / 2016 / Pharmacologic management of bone-related complications and bone metastases in postmenopausal women with hormone receptor-positive breast cancer / Breast Cancer(Dove Med Press) 8:73~82
Weinfurt KP / 2005 / The significance of skeletalrelated events for the health-related quality of life of patients with metastatic prostate cancer / Ann Oncol 16:579~584
Siegel RL / 2017 / Cancer statistics, 2017 / CA Cancer J Clin 67:7~30
Malvezzi M / 2012 / European cancer mortality predictions for the year 2012 / Ann Oncol 23:1044~1052
Yardley DA / 2016 / Pharmacologic management of bone-related complications and bone metastases in postmenopausal women with hormone receptor-positive breast cancer / Breast Cancer(Dove Med Press) 8:73~82
Weinfurt KP / 2005 / The significance of skeletalrelated events for the health-related quality of life of patients with metastatic prostate cancer / Ann Oncol 16:579~584
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