지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
Update on Monogenic Diabetes in Korea
Update on Monogenic Diabetes in Korea
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 627 - 639 (13page)
이용수
Update on Monogenic Diabetes in Korea
초록· 키워드
오류제보하기
Monogenic diabetes, including maturity-onset diabetes of the young, neonatal diabetes, and other rare forms of diabetes, results from a single gene mutation. It has been estimated to represent around 1% to 6% of all diabetes. With the advances in genome sequencing technology, it is possible to diagnose more monogenic diabetes cases than ever before. In Korea, 11 studies have identified several monogenic diabetes cases, using Sanger sequencing and whole exome sequencing since 2001. The recent largest study, using targeted exome panel sequencing, found a molecular diagnosis rate of 21.1% for monogenic diabetes in clinically suspected patients. Mutations in glucokinase (GCK), hepatocyte nuclear factor 1α (HNF1A), and HNF4A were most commonly found. Genetic diagnosis of monogenic diabetes is important as it determines the therapeutic approach required for patients and helps to identify affected family members. However, there are still many challenges, which include a lack of simple clinical criterion for selecting patients for genetic testing, difficulties in interpreting the genetic test results, and high costs for genetic testing. In this review, we will discuss the latest updates on monogenic diabetes in Korea, and suggest an algorithm to screen patients for genetic testing. The genetic tests and non-genetic markers for accurate diagnosis of monogenic diabetes will be also reviewed.
목차
등록된 정보가 없습니다.
참고문헌 (87)
참고문헌 신청
김성훈 / 2015 / Maturity-Onset Diabetes of the Young: What Do Clinicians Need to Know? / Diabetes and Metabolism Journal 39(6):468~477
Urakami T / 2019 / Maturity-onset diabetes of the young(MODY) : current perspectives on diagnosis and treatment / Diabetes Metab Syndr Obes 12:1047~1056
Tattersall RB / 1974 / Mild familial diabetes with dominant inheritance / Q J Med 43:339~357
Panzram G / 1981 / Heterogeneity of maturity onset diabetes at young age(MODY) / Lancet 2:986
Ledermann HM / 1995 / Is maturity onset diabetes at young age (MODY) more common in Europe than previously assumed? / Lancet 345:648
Urakami T / 2019 / Maturity-onset diabetes of the young(MODY) : current perspectives on diagnosis and treatment / Diabetes Metab Syndr Obes 12:1047~1056
Tattersall RB / 1974 / Mild familial diabetes with dominant inheritance / Q J Med 43:339~357
Panzram G / 1981 / Heterogeneity of maturity onset diabetes at young age(MODY) / Lancet 2:986
Ledermann HM / 1995 / Is maturity onset diabetes at young age (MODY) more common in Europe than previously assumed? / Lancet 345:648
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Higher Morbidity of Monogenic Inflammatory Bowel Disease Compared to the Adolescent Onset Inflammatory Bowel Disease
Pediatric Gastroenterology, Hepatology & Nutrition
2018 .01
-
Childhood diabetes in India
Annals of Pediatirc Endocrinology & Metabolism
2018 .01
-
Monogenic Autoimmune Diseases
대한류마티스학회지
2018 .01
-
Clinical and molecular characteristics of infantile-onset diabetes mellitus in Egypt
Annals of Pediatirc Endocrinology & Metabolism
2022 .09
-
The Relationship between Family History of Diabetes and Diabetes by BMI and Age in Korean Men and Women
대한의생명과학회지
2021 .12
-
Factors Associated with Participation in Diabetes Education: The Korea National Health and Nutrition Examination Survey 2007 to 2009
Diabetes and Metabolism Journal
2016 .01
-
Trends in the Diabetes Epidemic in Korea
Endocrinology and Metabolism
2015 .01
-
Diagnosis and Treatment of Monogenic Hypertension in Children
Yonsei Medical Journal
2023 .02
-
A homozygous mutation in the insulin gene (INS) causing autosomal recessive neonatal diabetes in Saudi families
Annals of Pediatirc Endocrinology & Metabolism
2020 .01
-
2023 Clinical Practice Guidelines for Diabetes Management in Korea: Full Version Recommendation of the Korean Diabetes Association
Diabetes and Metabolism Journal
2024 .07
-
Framingham Risk Score Assessment in Subjects with Pre-diabetes and Diabetes: A Cross-Sectional Study in Korea
Journal of Obesity & Metabolic Syndrome
2021 .09
-
Barrier Factors to the Completion of Diabetes Education in Korean Diabetic Adult Patients: Korea National Health and Nutrition Examination Surveys 2007-2012
Korean Journal of Family Medicine
2015 .01
-
Younger-Onset Diabetes: Is the Age of Onset More Important than the Duration of Diabetes?
Endocrinology and Metabolism
2024 .02
-
Molecular Diagnosis of Epilepsy in Clinical Practice
대한소아신경학회지
2016 .12
-
Thirst for Information and Needs Reflections of Type 2 Diabetes Patients Receiving Insulin Treatment in North-East Ethiopia: A Qualitative Exploration
예방의학회지
2021 .01
-
Clinical Characteristics of Diabetes in People with Mitochondrial DNA 3243A>G Mutation in Korea (Diabetes Metab J 2024;48:482-6)
Diabetes and Metabolism Journal
2024 .07
-
Diabetes and depression
영남의대학술지
2018 .01
-
Clinical aspects and management of osteoporosis and fragility fractures in patients with diabetes
Osteoporosis and Sarcopenia
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
첫번째 댓글을 남겨주세요.