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논문 기본 정보

자료유형
학술저널
저자정보
Kyu Sang Cho (Department of Plastic and Reconstructive Surgery Hanyang University College of Medicine Seoul Korea) Jung Soo Yoon (Department of Plastic and Reconstructive Surgery Hanyang University College of Medicine Seoul Korea) Hee Chang Ahn (Department of Plastic and Reconstructive Surgery Hanyang University College of Medicine Seoul Korea)
저널정보
대한수부외과학회 Archives of Hand and Microsurgery Archives of Hand and Microsurgery Vol.24 No.3
발행연도
2019.1
수록면
210 - 217 (8page)

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Purpose: Patients with secondary Raynaud’s syndrome experience severe pain and even ulceration of the fingertips, par-ticularly during the winter season. The aim of this retrospective review was to evaluate whether botulinum A toxin injec-tion before the winter season could prevent severe pain and complications in patients with secondary Raynaud’s syndrome.Methods: Patients (n=10) were injected with botulinum A toxin (25 U) at 14 points on each hand. Sex, age, number of treatments, underlying diseases, pre- and post-injection pain intensity and frequency, satisfaction with the injection, and complications were evaluated. Statistical analyses were performed using the Wilcoxon signed-rank test.Results: All patients had secondary Raynaud’s syndrome and were female, with mean age of 50.1 years. All patients showed an improvement in pain intensity after the injection. The frequency of pain per week improved after the injection in seven patients and remained the same in three patients. The mean satisfaction rating was 7.0 out of 10 points. Eight pa-tients were willing to reinject; however, two patients refused reinjection due to injectional pain. Two patients had tempo-rary weakness of the hand. Seven patients showed an improvement in cyanosis. Nine patients showed an protectiv effects in fingertip ulcerations.Conclusion: Botulinum A toxin injection in patients with secondary Raynaud’s syndrome before the winter season may provide substantial improvements in pain and ulceration, as the pain increases during the cold season. Furthermore, the protective effect of botulinum A toxin may also be helpful in preventing additional surgery.

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