지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Normal hemostasis is achieved by the concerted interactions of vascular endothelial cells, platelets, and plasma coagulation factors. The blood coagulation mechanism involves the regulated sequence of proteolytic activation of a series of blood coagulation zymogen factors. Some of these blood coagulation factors, either purified from human plasma or produced by recombinant DNA technologies, are used to treat patients with congenital or acquired deficiencies in coagulation factors. Furthermore, blood coagulation products are used for perioperative coagulation management and toical hemostatic agents to help control bleeding during surgery. Thus, the coagulant blood products have great medical importance to treat life-threatening bleeding disorders and serious medical conditions. This review provides an overview and summarizes the clinical use of coagulant blood products. (Korean J Blood Transfus 2021;32:11-21)
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Wright IS / 1958 / Nomenclature of blood clotting factors;acceptance by the International Committee on nomenclature of four factors, their characteristics and international number / Can Med Assoc J 80:659~661
Macfarlane RG / 1964 / An enzyme cascade in the blood clotting mechanism, and its function as a biochemical amplifier / Nature 202:498~499
Pool JG / 1965 / Production of highpotency concentrates of antihemophilic globulin in a closed-bag system / N Engl J Med 273:1443~1447
Kingdon HS / 2002 / An adventure in biotechnology : the development of haemophilia A therapeutics--from whole-blood transfusion to recombinant DNA to gene therapy / Biotechnol Appl Biochem 35:141~148
World Health Organization / 2007 / WHO Technical Report Series No 941. Annex 4. Recommendations for the production, control and regulation of human plasma for fractionation
Macfarlane RG / 1964 / An enzyme cascade in the blood clotting mechanism, and its function as a biochemical amplifier / Nature 202:498~499
Pool JG / 1965 / Production of highpotency concentrates of antihemophilic globulin in a closed-bag system / N Engl J Med 273:1443~1447
Kingdon HS / 2002 / An adventure in biotechnology : the development of haemophilia A therapeutics--from whole-blood transfusion to recombinant DNA to gene therapy / Biotechnol Appl Biochem 35:141~148
World Health Organization / 2007 / WHO Technical Report Series No 941. Annex 4. Recommendations for the production, control and regulation of human plasma for fractionation
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