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논문 기본 정보

자료유형
학술저널
저자정보
Young-Hoon Jeong (Chonnam National University Medical School) 이준 (조선대학교) Sang-Wook Kim (Chonbuk National University Medical School) Geom-Seog Seo (Wonkwang University College of Medicine) Hyun-Soo Kim (Chonnam National University Medical School) Young-Eun Joo (Chonnam National University Medical School)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.17 No.1
발행연도
2019.1
수록면
127 - 134 (8page)

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Background/Aims: Endoscopic submucosal dissection (ESD) is an advanced technique that can be used to treat precancerous and early colorectal neoplasms by facilitating en bloc resection regardless of tumor size. In our study, we investigated the clinicopathological feature and the treatment outcome of patients with colorectal laterally spreading tumors (LSTs) that were treated by ESD. Methods: The study enrolled all of 210 patients with colorectal LSTs who underwent ESD. Clinical outcomes were analyzed by retrospectively reviewing medical records. Results: A cancerous pit pattern (Vi/Vn) was more common in pseudo-depressed (PD) subtype than in flat elevated (FE) subtype. The incidence of adenocarcinoma in the PD subtype and nodular mixed (NM) subtypes was significantly higher than in the homogenous (HG) subtype and FE subtype. The en bloc and R0 resection rates were 89.0% and 85.7%, respectively. The bleeding and perforation rates were 5.2% and 1.9%, respectively. The mean procedure time was much longer in the PD subtype than in the FE subtype. The en bloc resection rate was significantly higher in the NM subtype than in the HG subtype. However, there were no statistically significant differences in mean procedure time, en bloc resection rate, R0 resection rate, bleeding rate, or perforation rate between LST-granular and LST-nongranular types. Conclusions: These results indicate that ESD is acceptable for treating colorectal LSTs concerning en bloc resection, curative resection, and risk of complications. Careful consideration is required for complete resection of the PD subtype and NM subtype because of their higher malignant potential. (Intest Res 2019;17:127-134)

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