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논문 기본 정보

자료유형
학술저널
저자정보
Jin-Ho Jheong (University of Ulsan) Suk-Kyung Hong (University of Ulsan) Tae-Hyun Kim (University of Ulsan)
저널정보
대한외상중환자외과학회 Journal of Acute Care Surgery Journal of Acute Care Surgery Vol.10 No.3
발행연도
2020.1
수록면
90 - 95 (6page)

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Purpose: Acute kidney injury (AKI) is an uncommon but serious complication after trauma. Theobjective of this study was to evaluate the clinical characteristics, risk factors, and outcomes of AKIafter trauma. Methods: A retrospective cohort study of 386 trauma patients who visited the emergencydepartment at the Asan Medical Center between January 2012 and December 2013 was performed. There were 322 patients included in this study. Patients were assigned into the AKI group and no AKIgroup. Regression analysis was performed to identify the factors associated with development of AKIfollowing trauma. Results: The overall incidence of AKI following trauma was 6%. There was no difference in patients`age, sex, and body weight between groups. Whereas there was a significant difference in InjurySeverity Score, Glasgow Coma Scale, presence of shock, need for a transfusion, lactic acid levels, andsevere rhabdomyolysis. In multivariate analysis, the independent risk factors associated with AKIafter trauma included the Injury Severity Score [odds ratio (OR) = 1.065, p < 0.01], presence of shock(OR = 3.949, p = 0.012), and severe rhabdomyolysis (OR = 4.475, p < 0.01). Patients in the AKI groupwere classified (according to the RIFLE criteria) as at Risk in 9 cases (43%), Injury present in 3 (14%),Failure in 7 (33%), Loss in 0 (0%) and End-stage in 2 (10%). Renal replacement therapy was requiredfor 10 patients (47%) in the AKI group and 4 of them (40%) underwent successful weaning. Hospitalmortality rate was higher in the AKI group (5/21, 23%) than the no AKI group (3/301, 1% ; p < 0.01). Conclusion: The development of AKI was associated with the severity of trauma, and traumaincreased mortality rates.

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