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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 1 - 7 (7page)
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초록· 키워드
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Objectives: This Clinical Guidance is aimed to help practitioners assess, diagnose and manage their patients with glucocorticoid-induced osteoporosis (GIO), using the best available evidence. Methods: A literature search using PubMed (MEDLINE) and The Cochrane Library identified all relevant articles on GIO and its assessment, diagnosis and treatment, from 2011, to update from the 2012 edition. The studies were assessed and the level of evidence assigned. For each statement, studies with the highest level of evidence were used to frame the recommendation. Results: Consider treatment early in all patients on glucocorticoids (GC) as fracture risk increases within 3e6 months of starting GC. The decision to start treatment for GIO depends on the presence of prior fracture, category of risk (as calculated using Fracture Risk Assessment Tool), daily dose and duration of GC treatment, age, and menopausal status. General measures include adequate calcium and vitamin D intake and reducing the dose of GC to the minimum required to achieve disease control. In patients on GC with osteoporotic fractures or confirmed osteoporosis on dual-energy X-ray absorptiometry, bisphosphonates are the first-line treatment. Treatment should be continued as long as patients remain on GC. Algorithms for the management of GIO in both pre- and post-menopausal women and men have been updated. Conclusions: In post-menopausal women and men above 50 years, bisphosphonates remain the mainstay of treatment in GIO. In pre-menopausal women and men below 50 years, bisphosphonates are recommended for those with a prevalent fracture or at very high risk only.
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참고문헌 (47)
참고문헌 신청
van Staa TP / 2000 / Utilisation of oral corticosteroids in the United Kingdom / Q J Med 93:105~111
Overman RA / 2013 / Prevalence of oral glucocorticoid usage in the United States: a general population perspective / Arthritis Care Res 65:294~298
Weiss RJ / 2010 / Increased fracture risk in patients with rheumatic disorders and other inflammatory diseases d a case-control study with 53,108 patients with fracture / J Rheumatol 37:2247~2250
van Staa TP / 2006 / Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis / Arthritis Rheum 54:3104~3112
van Staa TP / 2002 / The epidemiology of corticosteroid-induced osteoporosis: a meta-analysis / Osteoporos Int 13:777~787
Overman RA / 2013 / Prevalence of oral glucocorticoid usage in the United States: a general population perspective / Arthritis Care Res 65:294~298
Weiss RJ / 2010 / Increased fracture risk in patients with rheumatic disorders and other inflammatory diseases d a case-control study with 53,108 patients with fracture / J Rheumatol 37:2247~2250
van Staa TP / 2006 / Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis / Arthritis Rheum 54:3104~3112
van Staa TP / 2002 / The epidemiology of corticosteroid-induced osteoporosis: a meta-analysis / Osteoporos Int 13:777~787
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