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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 90 - 97 (8page)
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초록· 키워드
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Objectives: Osteoporosis and fracture impose a significant health care burden on the contemporary populations in developing countries. The Vietnam Osteoporosis Study (VOS) sought to assess the burden of osteoporosis and its comorbidities in men and women. Methods: The study was designed as a population-based family investigation in which families were randomly recruited from Ho Chi Minh City, Vietnam. Individuals were assessed for bone health, including bone mineral density (BMD) and body composition and trabecular and cortical bone properties by pQCT (peripheral quantitative computed tomography). Fasting blood samples were obtained for the analysis of plasma glucose, glycosylated hemoglobin, and bone turnover markers. Genomic DNA extraction from whole blood samples for further genetic and genomic analyses. Results: We have recruited more than 4157 individuals from 817 families. The average age of participants was 51, with approximately 45% of the individuals aged 50 years and older. Approximately 3% of participants were obese (body mass index 30 kg/m2), and 21% were overweight. Notably, 11% of participants aged 40 years and older were diabetic. Among those aged 50 years and older, approximately 14% of women and 5% of men had osteoporosis (i.e., femoral neck BMD T-scores 2.5). There were modest correlations between volumetric BMD and areal BMD. Conclusions: VOS is a major bone research project in Vietnam aimed at comprehensively documenting the burden osteoporosis, its co-occurrence of chronic diseases, and their underlying etiologies. The Study will make important contributions to the literature of bone health worldwide.
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참고문헌 (26)
참고문헌 신청
Nguyen ND / 2007 / Residual lifetime risk of fractures in women and men / J Bone Min Res 22:781~788
Kanis JA. / 2002 / Diagnosis of osteoporosis and assessment of fracture risk / Lancet 359:1929~1936
Cummings SR / 1989 / Lifetime risks of hip, Colles', or vertebral fracture and coronary heart disease among white postmenopausal women / Arch Intern Med 149:2445~2448
Center JR / 2007 / Risk of subsequent fracture after low-trauma fracture in men and women / JAMA 297:387~394
Bliuc D / 2009 / Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women / JAMA 301:513~521
Kanis JA. / 2002 / Diagnosis of osteoporosis and assessment of fracture risk / Lancet 359:1929~1936
Cummings SR / 1989 / Lifetime risks of hip, Colles', or vertebral fracture and coronary heart disease among white postmenopausal women / Arch Intern Med 149:2445~2448
Center JR / 2007 / Risk of subsequent fracture after low-trauma fracture in men and women / JAMA 297:387~394
Bliuc D / 2009 / Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women / JAMA 301:513~521
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