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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 101 - 108 (8page)
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Objective. This study examined lung involvement in patients with rheumatoid arthritis (RA) and identified factors associated with airway disease (AD) and interstitial lung disease (ILD). Methods. A total of 507 RA patients were enrolled in a cross-sectional study. Lung involvement was assessed by high-resolution computed tomography scan. The patient groups were classified according to normal, AD, and ILD. Multinomial logistic regression analysis was performed to identify factors associated with AD and ILD. Results. The most frequent lung involvement was AD (38.3%) followed by ILD (12.6%). Old age (adjust odds ratio [aOR] 2.58, 95% confidence interval [CI] 1.70 to 3.90 for AD; aOR 4.38, 95% CI 2.30 to 8.35 for ILD), male gender (aOR 2.57, 95% CI 1.22 to 5.42 for AD; aOR 5.48, 95% CI 2.20 to 13.65 for ILD) were factors associated with AD and ILD in RA patients. ILD was associated with short disease duration (aOR 0.30, 95% CI 0.14 to 0.62), AD was associated with high titers of anti-cyclic citrullinated peptides antibodies (anti-CCP; aOR 1.61, 95% CI 1.07 to 2.44). Conclusion. AD was the most frequent lung involvement in patients with RA. Old age and male gender were both associated with AD and ILD. Short disease duration was associated with ILD. High titers of anti-CCP was associated with AD. (J Rheum Dis 2016;23:101-108)
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참고문헌 (36)
참고문헌 신청
Carmona L / 2003 / Rheumatoid arthritis in Spain: occurrence of extra-articular manifestations and estimates of disease severity / Ann Rheum Dis 62:897~900
Cimmino MA / 2000 / Extra-articular manifestations in 587 Italian patients with rheumatoid arthritis / Rheumatol Int 19:213~217
Turesson C / 2003 / Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 years / Ann Rheum Dis 62:722~727
Demoruelle MK / 2014 / The lung may play a role in the pathogenesis of rheumatoid arthritis / Int J Clin Rheumtol 9:295~309
Yunt ZX / 2015 / Lung disease in rheumatoid arthritis / Rheum Dis Clin North Am 41:225~236
Cimmino MA / 2000 / Extra-articular manifestations in 587 Italian patients with rheumatoid arthritis / Rheumatol Int 19:213~217
Turesson C / 2003 / Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 years / Ann Rheum Dis 62:722~727
Demoruelle MK / 2014 / The lung may play a role in the pathogenesis of rheumatoid arthritis / Int J Clin Rheumtol 9:295~309
Yunt ZX / 2015 / Lung disease in rheumatoid arthritis / Rheum Dis Clin North Am 41:225~236
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