지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.4
- 수록면
- 61 - 70 (10page)
- DOI
- 10.4078/jrd.2022.29.2.61
이용수
초록· 키워드
오류제보하기
Rheumatoid arthritis (RA) is a common autoimmune disease that mainly affects the joints and systemic organs, such as the skin, eyes, heart, gastrointestinal tract, and lungs. In particular, among various pulmonary involvements, interstitial lung disease (ILD) is closely related to the selection of anti-rheumatic drugs and the long-term prognosis of patients with RA. Although the exact pathogenesis of RA-ILD is not well defined, several mechanistic pathways, similar to those of idiopathic pulmonary fibrosis, have been elucidated recently. Conversely, RA-related autoantibodies, including anti-cyclic citrullinated peptide antibody, are detectable in circulation and in the lungs, even in the absence of articular symptoms. RA-ILD can also predate years before the occurrence of joint symptoms. This evidence supports the fact that local dysregulated mucosal immunity in the lung causes systemic autoimmunity, resulting in clinically evident polyarthritis of RA. Because the early diagnosis of RA-ILD is important, imaging tests, such as computed tomography and pulmonary function tests, are being used for early diagnosis, but there is no clear guideline for the early diagnosis of RA-ILD and selection of optimal disease-modifying anti-rheumatic drugs for the treatment of patients with RA with ILD. In addition, the efficacy of nintedanib, a new anti-fibrotic agent, for RA-ILD treatment, has been investigated recently. This review collectively discusses the basic and clinical aspects, such as pathogenesis, animal models, diagnosis, and treatment, of RA-ILD.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Epidemiology of Rheumatoid Arthritis in Korea
대한류마티스학회지
2021 .01
-
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 5. Connective Tissue Disease Associated Interstitial Lung Disease
Tuberculosis and Respiratory Diseases
2019 .01
-
류마티스관절염에 동반된 폐침범의 양상과 관련인자 분석
대한류마티스학회지
2016 .01
-
간질성 폐질환의 진단 및 치료: 특발성 폐섬유증을 중심으로 알아보기
대한의사협회지
2020 .01
-
자가면역 관련 사이질폐질환 치료의 최신지견
대한의사협회지
2021 .01
-
Gefitinib-Induced Interstitial Lung Disease in Korean Lung Cancer Patients
Cancer Research and Treatment
2016 .01
-
류마티스관절염 치료지침 업데이트
대한내과학회지
2022 .04
-
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 1. Introduction
Tuberculosis and Respiratory Diseases
2019 .01
-
Rheumatoid arthritis in tight disease control is no longer risk of bone mineral density loss
Osteoporosis and Sarcopenia
2020 .01
-
Mortality in Korean Patients With Rheumatoid Arthritis
대한류마티스학회지
2021 .01
-
Lessons From the Success and Failure of Targeted Drugs for Rheumatoid Arthritis: Perspectives for Effective Basic and Translational Research
Immune Network
2022 .02
-
Hypereosinophilic Syndrome Associated with the Onset of Rheumatoid Arthritis: A Case Report
대한류마티스학회지
2017 .01
-
Associations of periodontal status in periodontitis and rheumatoid arthritis patients
Journal of Periodontal & Implant Science
2021 .01
-
Adult Stem Cell Treatment for Rheumatoid Arthritis
대한류마티스학회지
2018 .01
-
Characteristics of Appendicular Tissue Components in Patients with Rheumatoid Arthritis
대한골대사학회지
2020 .01
-
류마티스관절염의 약물치료
대한의사협회지
2017 .01
-
Pediatric Case Report on an Interstitial Lung Disease with a Novel Mutation of SFTPC Successfully Treated with Lung Transplantation
Journal of Korean Medical Science
2018 .01
-
Association of Serum Biomarkers With Pulmonary Involvement of Rheumatoid Arthritis Interstitial Lung Disease: From KORAIL Cohort Baseline Data
대한류마티스학회지
2021 .10
-
Proteomics in Rheumatoid Arthritis Research
Immune Network
2015 .08
-
Risk Factors for the Development and Progression of Atlantoaxial Subluxation in Surgically Treated Rheumatoid Arthritis Patients, Considering the Time Interval between Rheumatoid Arthritis Diagnosis and Surgery
대한신경외과학회지
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0