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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 1 - 8 (8page)
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Background: To investigate the clinicopathological characteristics of urinary bladder tumors, a rare malignancy, in patients 20 years or younger. Methods: Using a retrospective chart review among patients who received bladder surgery at 2 institutions between July 1996 and January 2013, we analyzed the clinicopathological characteristics of urinary bladder tumors in 21 pediatric patients (male:female = 4.25:1.00; mean age, 12.1 years). Results: Pathology revealed 9 urothelial tumors, 6 rhabdomyosarcomas, 1 low- grade leiomyosarcoma, 1 large cell neuroendocrine carcinoma, 1 inflammatory myofibroblastic tumor, and 3 cases of chronic inflammation without tumors (including 1 xanthogranulomatous inflammation). Urothelial tumors (mean patient age, 16.0 years) were benign or low-grade; and only transurethral resection of the bladder tumor was necessary for treatment. Patients with rhabdomyosarcomas (mean age, 5 years) underwent radiotherapy (if unresectable) or transurethral resection of the bladder tumor (if resectable), after chemotherapy. Of these patients, 2 underwent radical cystectomy, with the remaining patients not receiving a cystectomy. With the exception of one patient, all patients are currently alive and recurrence-free. Conclusion: Urothelial tumors were the most commonly found pediatric bladder tumor, with embryonal rhabdomyosarcoma being the second most common. Urothelial tumors are common in relatively older age. Since urothelial tumors in children typically have a good prognosis and rarely recur, transurethral resection of the bladder tumor is the treatment of choice. Rhabdomyosarcomas are common in younger patients. Since rhabdomyosarcoma is generally chemosensitive, chemotherapy and radiotherapy are the treatment of choice for bladder preservation in these patients.
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참고문헌 (26)
참고문헌 신청
Kutarski PW / 1993 / Transitional cell carcinoma of the bladder in young adults / Br J Urol 72(5):749~755
Javadpour N / 1969 / Primary epithelial tumors of the bladder in the first two decades of life / J Urol 101(5):706~710
Paner GP / 2011 / Urothelial neoplasms of the urinary bladder occurring in young adult and pediatric patients: a comprehensive review of literature with implications for patient management / Adv Anat Pathol 18(1):79~89
Stanton ML / 2013 / Urothelial tumors of the urinary bladder in young patients: a clinicopathologic study of 59 cases / Arch Pathol Lab Med 137(10):1337~1341
Alanee S / 2010 / Bladder malignancies in children aged <18 years: results from the Surveillance, Epidemiology and End Results database / BJU Int 106(4):557~560
Javadpour N / 1969 / Primary epithelial tumors of the bladder in the first two decades of life / J Urol 101(5):706~710
Paner GP / 2011 / Urothelial neoplasms of the urinary bladder occurring in young adult and pediatric patients: a comprehensive review of literature with implications for patient management / Adv Anat Pathol 18(1):79~89
Stanton ML / 2013 / Urothelial tumors of the urinary bladder in young patients: a clinicopathologic study of 59 cases / Arch Pathol Lab Med 137(10):1337~1341
Alanee S / 2010 / Bladder malignancies in children aged <18 years: results from the Surveillance, Epidemiology and End Results database / BJU Int 106(4):557~560
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