지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 1 - 6 (6page)
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초록· 키워드
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We validated the diagnostic performance of a previously developed blood-based 7-protein biomarker panel, AptoDetect™-Lung (Aptamer Sciences Inc., Pohang, Korea) using modified aptamer-based proteomic technology for lung cancer detection. Non-small cell lung cancer (NSCLC), 200 patients and benign nodule controls, 200 participants were enrolled. In a high-risk population corresponding to ≥ 55 years of age and ≥ 30 pack-years, the diagnostic performance was improved, showing 73.3% sensitivity and 90.5% specificity with an area under the curve of 0.88. AptoDetect™-Lung (Aptamer Sciences Inc.) offers the best validated performance to discriminate NSCLC from benign nodule controls in a high-risk population and could play a complementary role in lung cancer screening.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Siegel RL / 2016 / Cancer statistics, 2016 / CA Cancer J Clin 66(1):7~30
정규원 / 2014 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011 / Cancer Research and Treatment 46(2):109~123
Aberle DR / 2011 / Reduced lung-cancer mortality with low-dose computed tomographic screening / N Engl J Med 365(5):395~409
Church TR / 2013 / Results of initial low-dose computed tomographic screening for lung cancer / N Engl J Med 368(21):1980~1991
Moyer VA / 2014 / Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement / Ann Intern Med 160(5):330~338
정규원 / 2014 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011 / Cancer Research and Treatment 46(2):109~123
Aberle DR / 2011 / Reduced lung-cancer mortality with low-dose computed tomographic screening / N Engl J Med 365(5):395~409
Church TR / 2013 / Results of initial low-dose computed tomographic screening for lung cancer / N Engl J Med 368(21):1980~1991
Moyer VA / 2014 / Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement / Ann Intern Med 160(5):330~338
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