지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 278 - 285 (8page)
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초록· 키워드
오류제보하기
Background: This prospective randomized double-blinded study was designed to compare the efficacy of a combination of high dose metoclopramide and dexamethasone with that of haloperidol, midazolam and dexamethasone, for the prevention of postoperative nausea and vomiting (PONV) in patients scheduled for laparoscopic gynecologic surgery who are receiving fentanyl intravenous-patient controlled analgesia. Methods: The subjects were randomly allocated to either group M (20 mg metoclopramide and 10 mg dexamethasone was administered at induction, n = 35) or group H (1 mg haloperidol, 3 mg midazolam and 10 mg dexamethasone were administered at induction, n = 35). The incidence of PONV and the severity (measured by numeric rating scale) of the patients’ nausea and pain were evaluated at 6 hours, 24 hours, and 48 hours, postoperatively. Results: The overall incidence of the PONV was not significantly different between the two groups during the 48 hours period (group M: 21% vs. group H: 12%). The severity of the nausea and pain were similar between the two groups. Conclusions: The prophylactic use of a combination of 1 mg haloperidol, 3 mg midazolam and 10 mg dexamethasone is as effective and inexpensive as 20 mg metoclopramide and 10 mg dexamethasone to prevent PONV.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Fortier J / 1998 / Unanticipated admission after ambulatory surgery--a prospective study / Can J Anaesth 45:612~619
Apfel CC / 1999 / A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers / Anesthesiology 91:693~700
Gan TJ / 2014 / Consensus guidelines for the management of postoperative nausea and vomiting / Anesth Analg 118:85~113
Wallenborn J / 2006 / Prevention of postoperative nausea and vomiting by metoclopramide combined with dexamethasone: randomised double blind multicentre trial / BMJ 333:324
지영석 / 2010 / Prophylactic antiemetic effects in gynecologic patients receiving fentanyl IV-patient controlled analgesia: comparison of combined treatment with ondansetron and dexamethasone with metoclopramide and dexamethasone / Korean Journal of Anesthesiology 59(5):335~339
Apfel CC / 1999 / A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers / Anesthesiology 91:693~700
Gan TJ / 2014 / Consensus guidelines for the management of postoperative nausea and vomiting / Anesth Analg 118:85~113
Wallenborn J / 2006 / Prevention of postoperative nausea and vomiting by metoclopramide combined with dexamethasone: randomised double blind multicentre trial / BMJ 333:324
지영석 / 2010 / Prophylactic antiemetic effects in gynecologic patients receiving fentanyl IV-patient controlled analgesia: comparison of combined treatment with ondansetron and dexamethasone with metoclopramide and dexamethasone / Korean Journal of Anesthesiology 59(5):335~339
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